| Long name: |
FITC Conjugated, PLCZ1 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
PLCZ1 |
| Specificity: |
This is a highly specific antibody against PLCZ1 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
380-430/608 |
| Subcellular location: |
Nucleus, Cytoplasm |
| Source: |
KLH conjugated synthetic peptide derived from human PLCZ1 |
| Gene ID number: |
89869 |
| Swiss Prot: |
Q86YW0 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
In vitro, Is therefore a strong candidate for the egg-activating soluble sperm factor that is transferred from the sperm into the egg cytoplasm following gamete membrane fusion, May exert an inhibitory effect on phospholipase-C-coupled processes that depend on calcium ions and protein kinase C, Triggers intracellular Ca(2+) oscillations in oocytes solely during M phase and is involved in inducing oocyte activation and initiating embryonic development up to the blastocyst stage, hydrolyzes PtdIns(4, including CFTR trafficking and function, 4, 5)P2 in a Ca(2+)-dependent manner, 5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes, The production of the second messenger molecules diacylglycerol (DAG) and inositol 1 |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
NYD-SP27 PLCzeta |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
PLCZ1 Conjugated |
| Short name: |
FITC Conjugated, PLCZ1 Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, PLCZ1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
19218 |
| Gene: |
PLCZ1 |
More about : PLCZ1 |
| Long gene name: |
phospholipase C zeta 1 |
| Synonyms gene name: |
phospholipase C, zeta 1 |
| Locus: |
12p12, 3 |
| Discovery year: |
2002-09-13 |
| GenBank acession: |
AY035866 |
| Entrez gene record: |
89869 |
| Pubmed identfication: |
12117804 |
| RefSeq identity: |
NM_033123 |
| Classification: |
Phospholipases C2 domain containing phospholipases EF-hand domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000168937 |