| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
BAG2 |
| Specificity: |
This antibody reacts specifically with BAG2 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human BAG2 |
| Gene ID: |
9532 |
| Swiss Prot: |
O95816 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner, All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions, BAG2, The BAG domains of BAG1, The predicted BAG2 protein contains 211 amino acids, [provided by RefSeq], and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells, BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Also known as: |
BAG2 Polyclonal Antibody |
| Other name: |
Anti-BAG2 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
BAG2 |
| Short name: |
Anti-BAG2 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-B-cell CLL/lymphoma 2-associated athanogene 2 (polyclonal) |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
BAG-2 and dJ417I1, BAG2 and IDBG-628617 and ENSBTAG00000005355 and 506107, BAG2 and IDBG-91571 and ENSG00000112208 and 9532, Bag2 and IDBG-140714 and ENSMUSG00000042215 and 213539, chaperone binding, multiple, this GO :0005515 and protein binding and molecular function this GO :0006457 and protein folding and biological process this GO :0019538 and protein metabolic process and biological process this GO :0051087 and chaperone binding and molecular function, this GO :0005515 : protein binding, this GO :0005515 : protein binding and also this GO :0051087 : chaperone binding, this GO :0051087 : chaperone binding, 2, BCL2-associated athanogene 2 |
| Identity: |
938 |
| Gene: |
BAG2 |
More about : BAG2 |
| Long gene name: |
BCL2 associated athanogene 2 |
| Locus: |
6p12, 1 |
| Discovery year: |
1999-04-23 |
| GenBank acession: |
AF095192 |
| Entrez gene record: |
9532 |
| Pubmed identfication: |
9873016 |
| Classification: |
BCL2 associated athanogene family |
| Havana BLAST/BLAT: |
OTTHUMG00000014919 |