| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
APOC3 |
| Specificity: |
This antibody reacts specifically with APOC3 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Secreted |
| Antigen Source: |
KLH conjugated synthetic peptide derived from rat Apolipoprotein CIII |
| Gene ID: |
11814 |
| Swiss Prot: |
P33622 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Rat (Rattus norvegicus), Mouse (Mus musculus) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Impairs the lipolysis of TRLs by inhibiting lipoprotein lipase and the hepatic uptake of TRLs by remnant receptors, Intracellularly, Plays a multifaceted role in triglyceride homeostasis, attenuates hydrolysis and clearance of triglyceride-rich lipoproteins (TRLs), extracellularly, promotes hepatic very low density lipoprotein 1 (VLDL1) assembly and secretion, Component of triglyceride-rich very low density lipoproteins (VLDL) and high density lipoproteins (HDL) in plasma |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Also known as: |
APOC3 Polyclonal Antibody |
| Other name: |
Anti-APOC3 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
APOC3 |
| Short name: |
Anti-APOC3 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-apolipoprotein C-III (polyclonal) |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
APOC3 and IDBG-630792 and ENSBTAG00000012398 and 408009, APOC3 and IDBG-72562 and ENSG00000110245 and 345, APOCIII and HALP2, Apoc3 and IDBG-161220 and ENSMUSG00000032081 and 11814, Extracellular, high-density lipoprotein particle receptor binding, this GO :0001523 and retinoid metabolic process and biological process this GO :0005543 and phospholipid binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0005769 and early endosome and cellular component this GO :0006641 and triglyceride metabolic process and biological process this GO :0006642 and triglyceride mobilization and biological process this GO :0006869 and lipid transport and biological process this GO :0006954 and inflammatory response and biological process this GO :0007186 and G-protein coupled receptor signaling pathway and biological process this GO :0007584 and response to nutrient and biological process this GO :0007603 and phototransduction, this GO :0005543 : phospholipid binding, this GO :0005543 : phospholipid binding and also this GO :0008289 : lipid binding and also this GO :0015485 : cholesterol binding and also this GO :0030234 : enzyme regulator activity and also this GO :0055102 : lipase inhibitor activity and also this GO :0070653 : high-density lipoprotein particle receptor binding, this GO :0008289 : lipid binding, this GO :0015485 : cholesterol binding, this GO :0030234 : enzyme regulator activity, this GO :0055102 : lipase inhibitor activity, this GO :0070653 : high-density lipoprotein particle receptor binding, visible light and biological process this GO :0008203 and cholesterol metabolic process and biological process this GO :0008289 and lipid binding and molecular function this GO :0010897 and negative regulation of triglyceride catabolic process and biological process this GO :0010903 and negative regulation of very-low-density lipoprotein particle remodeling and biological process this GO :0010916 and negative regulation of very-low-density lipoprotein particle clearance and biological process this GO :0010987 and negative regulation of high-density lipoprotein particle clearance and biological process this GO :0010989 and negative regulation of low-density lipoprotein particle clearance and biological process this GO :0015485 and cholesterol binding and molecular function this GO :0019433 and triglyceride catabolic process and biological process this GO :0030234 and enzyme regulator activity and molecular function this GO :0032489 and regulation of Cdc42 protein signal transduction and biological process this GO :0033344 and cholesterol efflux and biological process this GO :0033700 and phospholipid efflux and biological process this GO :0034361 and very-low-density lipoprotein particle and cellular component this GO :0034363 and intermediate-density lipoprotein particle and cellular component this GO :0034366 and spherical high-density lipoprotein particle and cellular component this GO :0034375 and high-density lipoprotein particle remodeling and biological process this GO :0034379 and very-low-density lipoprotein particle assembly and biological process this GO :0034382 and chylomicron remnant clearance and biological process this GO :0042157 and lipoprotein metabolic process and biological process this GO :0042493 and response to drug and biological process this GO :0042627 and chylomicron and cellular component this GO :0042632 and cholesterol homeostasis and biological process this GO :0042953 and lipoprotein transport and biological process this GO :0043434 and response to peptide hormone and biological process this GO :0043691 and reverse cholesterol transport and biological process this GO :0044281 and small molecule metabolic process and biological process this GO :0045717 and negative regulation of fatty acid biosynthetic process and biological process this GO :0045833 and negative regulation of lipid metabolic process and biological process this GO :0048261 and negative regulation of receptor-mediated endocytosis and biological process this GO :0050995 and negative regulation of lipid catabolic process and biological process this GO :0051005 and negative regulation of lipoprotein lipase activity and biological process this GO :0055102 and lipase inhibitor activity and molecular function this GO :0060621 and negative regulation of cholesterol import and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0070328 and triglyceride homeostasis and biological process this GO :0070653 and high-density lipoprotein particle receptor binding and molecular function this GO :0071333 and cellular response to glucose stimulus and biological process, apolipoprotein C-III |
| Identity: |
610 |
| Gene: |
APOC3 |
More about : APOC3 |
| Long gene name: |
apolipoprotein C3 |
| Synonyms gene name: |
apolipoprotein C-III |
| Locus: |
11q23, 3 |
| Discovery year: |
2001-06-22 |
| GenBank acession: |
X01388 |
| Entrez gene record: |
345 |
| RefSeq identity: |
NM_000040 |
| Classification: |
Apolipoproteins |
| Havana BLAST/BLAT: |
OTTHUMG00000046115 |