| Long name: |
APOC3 Primary Polyclonal Antibody |
| Also known as: |
APOC3 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
APOC3 |
| Specificity: |
This is a highly specific antibody against APOC3 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
55-100/101 |
| Subcellular location: |
Secreted |
| Source: |
KLH conjugated synthetic peptide derived from rat Apolipoprotein CIII |
| Gene ID number: |
11814 |
| Swiss Prot: |
P33622 |
| Tested Applications: |
IF(IHC-P), IHC-P |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500) |
| Cross reactivity: |
Rat, Mouse |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Impairs the lipolysis of TRLs by inhibiting lipoprotein lipase and the hepatic uptake of TRLs by remnant receptors, Intracellularly, Plays a multifaceted role in triglyceride homeostasis, attenuates hydrolysis and clearance of triglyceride-rich lipoproteins (TRLs), extracellularly, promotes hepatic very low density lipoprotein 1 (VLDL1) assembly and secretion, Component of triglyceride-rich very low density lipoproteins (VLDL) and high density lipoproteins (HDL) in plasma |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
Apoc3, Apolipoprotein C-III, Apolipoprotein C3, apoC-III, apo-CIII |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
APOC3 |
| Short name: |
APOC3 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
apolipoprotein C-III (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
APOC3 and IDBG-630792 and ENSBTAG00000012398 and 408009, APOC3 and IDBG-72562 and ENSG00000110245 and 345, APOCIII and HALP2, Apoc3 and IDBG-161220 and ENSMUSG00000032081 and 11814, Extracellular, high-density lipoprotein particle receptor binding, this GO :0001523 and retinoid metabolic process and biological process this GO :0005543 and phospholipid binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0005769 and early endosome and cellular component this GO :0006641 and triglyceride metabolic process and biological process this GO :0006642 and triglyceride mobilization and biological process this GO :0006869 and lipid transport and biological process this GO :0006954 and inflammatory response and biological process this GO :0007186 and G-protein coupled receptor signaling pathway and biological process this GO :0007584 and response to nutrient and biological process this GO :0007603 and phototransduction, this GO :0005543 : phospholipid binding, this GO :0005543 : phospholipid binding and also this GO :0008289 : lipid binding and also this GO :0015485 : cholesterol binding and also this GO :0030234 : enzyme regulator activity and also this GO :0055102 : lipase inhibitor activity and also this GO :0070653 : high-density lipoprotein particle receptor binding, this GO :0008289 : lipid binding, this GO :0015485 : cholesterol binding, this GO :0030234 : enzyme regulator activity, this GO :0055102 : lipase inhibitor activity, this GO :0070653 : high-density lipoprotein particle receptor binding, visible light and biological process this GO :0008203 and cholesterol metabolic process and biological process this GO :0008289 and lipid binding and molecular function this GO :0010897 and negative regulation of triglyceride catabolic process and biological process this GO :0010903 and negative regulation of very-low-density lipoprotein particle remodeling and biological process this GO :0010916 and negative regulation of very-low-density lipoprotein particle clearance and biological process this GO :0010987 and negative regulation of high-density lipoprotein particle clearance and biological process this GO :0010989 and negative regulation of low-density lipoprotein particle clearance and biological process this GO :0015485 and cholesterol binding and molecular function this GO :0019433 and triglyceride catabolic process and biological process this GO :0030234 and enzyme regulator activity and molecular function this GO :0032489 and regulation of Cdc42 protein signal transduction and biological process this GO :0033344 and cholesterol efflux and biological process this GO :0033700 and phospholipid efflux and biological process this GO :0034361 and very-low-density lipoprotein particle and cellular component this GO :0034363 and intermediate-density lipoprotein particle and cellular component this GO :0034366 and spherical high-density lipoprotein particle and cellular component this GO :0034375 and high-density lipoprotein particle remodeling and biological process this GO :0034379 and very-low-density lipoprotein particle assembly and biological process this GO :0034382 and chylomicron remnant clearance and biological process this GO :0042157 and lipoprotein metabolic process and biological process this GO :0042493 and response to drug and biological process this GO :0042627 and chylomicron and cellular component this GO :0042632 and cholesterol homeostasis and biological process this GO :0042953 and lipoprotein transport and biological process this GO :0043434 and response to peptide hormone and biological process this GO :0043691 and reverse cholesterol transport and biological process this GO :0044281 and small molecule metabolic process and biological process this GO :0045717 and negative regulation of fatty acid biosynthetic process and biological process this GO :0045833 and negative regulation of lipid metabolic process and biological process this GO :0048261 and negative regulation of receptor-mediated endocytosis and biological process this GO :0050995 and negative regulation of lipid catabolic process and biological process this GO :0051005 and negative regulation of lipoprotein lipase activity and biological process this GO :0055102 and lipase inhibitor activity and molecular function this GO :0060621 and negative regulation of cholesterol import and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0070328 and triglyceride homeostasis and biological process this GO :0070653 and high-density lipoprotein particle receptor binding and molecular function this GO :0071333 and cellular response to glucose stimulus and biological process, apolipoprotein C-III |
| Identity: |
610 |
| Gene: |
APOC3 |
More about : APOC3 |
| Long gene name: |
apolipoprotein C3 |
| Synonyms gene name: |
apolipoprotein C-III |
| Locus: |
11q23, 3 |
| Discovery year: |
2001-06-22 |
| GenBank acession: |
X01388 |
| Entrez gene record: |
345 |
| RefSeq identity: |
NM_000040 |
| Classification: |
Apolipoproteins |
| Havana BLAST/BLAT: |
OTTHUMG00000046115 |