| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
beta 2 Defensin |
| Specificity: |
This antibody reacts specifically with beta 2 Defensin |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Secreted |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human beta 2 Defensin |
| Gene ID: |
1673 |
| Swiss Prot: |
O15263 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Beta-defensins are developmentally regulated, Human b-defensin 2 is locally regulated by inflammation and is the first member of the b-defensin family that is locally inducible by inflammation, Produced in mucosal epithelia and neutrophils of several species, The murine homolog of human b-defensin 2, The unique murine b-defensin 2 (Defb2) is not expressed in airways of untreated mice, and hBD in human) are small cationic peptides with broad-spectrum antimicrobial activity, but is upregulated in the airways by lipopolysaccharide and may contribute to host defense at the mucosal surface of the airways, is present in the respiratory system and in low levels in the epithelial cells of the intestine and lung, which is called b-defensin 3, Beta-defensins (also designated BD |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Also known as: |
beta 2 Defensin Polyclonal Antibody |
| Other name: |
Anti-beta 2 Defensin Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
beta 2 Defensin |
| Short name: |
Anti-beta 2 Defensin (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-b 2 Defensin (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
30193 |
| Gene: |
DEFB4B |
More about : DEFB4B |
| Long gene name: |
defensin beta 4B |
| Synonyms gene: |
DEFB4P |
| Synonyms gene name: |
beta 4, beta 4B , defensin, pseudogene defensin |
| Synonyms name: |
beta defensin 2 beta defensin-2 beta-defensin 2 |
| Locus: |
8p23, 1 |
| Discovery year: |
2005-02-25 |
| Entrez gene record: |
100289462 |
| Classification: |
Defensins, beta |
| Havana BLAST/BLAT: |
OTTHUMG00000143857 |