| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
Defensin alpha 4 |
| Specificity: |
This antibody reacts specifically with Defensin alpha 4 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human Defensin alpha 4 |
| Gene ID: |
1669 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif, Several alpha defensin genes are clustered on chromosome 8, The protein encoded by this gene, They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, This gene differs from other genes of this family by an extra 83-base segment that is apparently the result of a recent duplication within the coding region, [provided by RefSeq], alpha 4, and vagina, defensin, is found in the neutrophils, it exhibits corticostatic activity and inhibits corticotropin stimulated corticosterone production, respiratory tract, urinary tract, Defensins are a family of microbicidal and cytotoxic peptides thought to be involved in host defense |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
HP-4 |
| Also known as: |
Defensin alpha 4 Polyclonal Antibody |
| Other name: |
Anti-Defensin alpha 4 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
Defensin alpha 4 |
| Short name: |
Anti-Defensin alpha 4 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-Defensin a 4 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
2763 |
| Gene: |
DEFA4 |
More about : DEFA4 |
| Long gene name: |
defensin alpha 4 |
| Synonyms gene: |
DEF4 |
| Synonyms gene name: |
alpha 4, corticostatin , defensin |
| Locus: |
8p23, 1 |
| Discovery year: |
1993-11-05 |
| GenBank acession: |
X65977 |
| Entrez gene record: |
1669 |
| Pubmed identfication: |
8469233 |
| RefSeq identity: |
NM_001925 |
| Classification: |
Defensins, alpha |
| Havana BLAST/BLAT: |
OTTHUMG00000090382 |