| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
Synaptotagmin |
| Specificity: |
This antibody will cross-react with Synaptotagmin 2 and Synaptotagmin |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Cytoplasm |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human Synaptotagmin 1 |
| Gene ID: |
6857 |
| Swiss Prot: |
P21579 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
A Ca(2+)-dependent interaction between synaptotagmin and putative receptors for activated protein kinase C has also been reported, It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone, It can bind to at least three additional proteins in a Ca(2+)-independent manner, syntaxin and AP2, these are neurexins, May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
yt14r CHR14SYT Strep14 |
| Also known as: |
Synaptotagmin Polyclonal Antibody |
| Other name: |
Anti-Synaptotagmin Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
Synaptotagmin |
| Short name: |
Anti-Synaptotagmin (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-Synaptotagmin (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
23142 |
| Gene: |
SYT16 |
More about : SYT16 |
| Long gene name: |
synaptotagmin 16 |
| Synonyms gene: |
SYT14L |
| Synonyms gene name: |
synaptotagmin XIV-like synaptotagmin XVI |
| Synonyms name: |
synaptotagmin XIV-related chr14 synaptotagmin |
| Locus: |
14q23, 2 |
| Discovery year: |
2003-09-18 |
| GenBank acession: |
BC040924 |
| Entrez gene record: |
83851 |
| Pubmed identfication: |
11543631 |
| RefSeq identity: |
NM_031914 |
| Classification: |
Synaptotagmins |
| Havana BLAST/BLAT: |
OTTHUMG00000171106 |