| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
Synaptotagmin XI |
| Specificity: |
This antibody reacts specifically with Synaptotagmin XI |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human Synaptotagmin XI |
| Gene ID: |
23208 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Defects in the gene encoding Synaptotagmin XI are implicated in a number of neurological disorders, Like other Synaptotagmin proteins, Synaptotagmin XI, Synaptotagmin XI contains two C2 domains through which it can bind either three calcium ions or the zinc-finger protein Parkin (a juvenile Parkinsonâ, Synaptotagmin XI is involved in the calcium-dependent exocytosis of secretory vesicles and is thought to act as a calcium sensor during vesicular trafficking, also known as SYT11 (Synaptotagmin-11), including schizophrenia and Parkinsonâ, is a 431 amino acid protein that localizes to the membrane and is expressed ubiquitously with highest expression in brain and lung, the latter of which causes the polyubiquitination and subsequent degradation of Synaptotagmin XI by the proteasome complex, &euro, &euro, &trade, &trade, Synaptotagmins are a large family of synaptic vesicle type III integral membrane proteins that function as regulators of both exocytosis and endocytosis and are involved in neurotransmitter secretion from small secretory vesicles, s disease, s disease gene product) |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
KIAA0080 MGC10881 MGC17226 DKFZp781D015 |
| Also known as: |
Synaptotagmin XI Polyclonal Antibody |
| Other name: |
Anti-Synaptotagmin XI Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
Synaptotagmin XI |
| Short name: |
Anti-Synaptotagmin XI (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-Synaptotagmin XI (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
19239 |
| Gene: |
SYT11 |
More about : SYT11 |
| Long gene name: |
synaptotagmin 11 |
| Synonyms gene name: |
synaptotagmin XI |
| Locus: |
1q22 |
| Discovery year: |
2002-09-20 |
| GenBank acession: |
D38522 |
| Entrez gene record: |
23208 |
| Pubmed identfication: |
11543631 |
| RefSeq identity: |
NM_152280 |
| Classification: |
Synaptotagmins |
| Havana BLAST/BLAT: |
OTTHUMG00000014105 |