| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
ITGB4 |
| Specificity: |
This antibody reacts specifically with ITGB4 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Extracellular |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human ITGB4 |
| Gene ID: |
3691 |
| Swiss Prot: |
P16144 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Is required for the regulation of keratinocyte polarity and motility, Plays a critical structural role in the hemidesmosome of epithelial cells, Integrin alpha-6/beta-4 is a receptor for laminin |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
CD104 |
| Also known as: |
ITGB4 Polyclonal Antibody |
| Other name: |
Anti-ITGB4 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
ITGB4 |
| Short name: |
Anti-ITGB4 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, b 4 (polyclonal), antibody to-integrin |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
CD104, Cell surfaces, ITGB4 and IDBG-643160 and ENSBTAG00000018169 and, ITGB4 and IDBG-68784 and ENSG00000132470 and 3691, Itgb4 and IDBG-214382 and ENSMUSG00000020758 and 192897, beta 4, protein binding, this GO :0001664 and G-protein coupled receptor binding and molecular function this GO :0004872 and receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005604 and basement membrane and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006914 and autophagy and biological process this GO :0007154 and cell communication and biological process this GO :0007155 and cell adhesion and biological process this GO :0007160 and cell-matrix adhesion and biological process this GO :0007229 and integrin-mediated signaling pathway and biological process this GO :0007275 and multicellular organismal development and biological process this GO :0008305 and integrin complex and cellular component this GO :0009611 and response to wounding and biological process this GO :0009925 and basal plasma membrane and cellular component this GO :0009986 and cell surface and cellular component this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0030056 and hemidesmosome and cellular component this GO :0030198 and extracellular matrix organization and biological process this GO :0031252 and cell leading edge and cellular component this GO :0031581 and hemidesmosome assembly and biological process this GO :0034329 and cell junction assembly and biological process this GO :0043235 and receptor complex and cellular component this GO :0046847 and filopodium assembly and biological process this GO :0048870 and cell motility and biological process this GO :0070062 and extracellular vesicular exosome and cellular component, this GO :0001664 : G-protein coupled receptor binding, this GO :0001664 : G-protein coupled receptor binding and also this GO :0004872 : receptor activity and also this GO :0005515 : protein binding, this GO :0004872 : receptor activity, this GO :0005515 : protein binding, integrin |
| Identity: |
6158 |
| Gene: |
ITGB4 |
More about : ITGB4 |
| Long gene name: |
integrin subunit beta 4 |
| Synonyms gene name: |
beta 4 , integrin |
| Locus: |
17q25, 1 |
| Discovery year: |
1991-08-06 |
| Entrez gene record: |
3691 |
| Pubmed identfication: |
2070796 |
| Classification: |
Integrin beta subunits CD molecules Fibronectin type III domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000179814 |