| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
G protein beta 3/GNB3 |
| Specificity: |
This antibody reacts specifically with G protein beta 3/GNB3 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human G protein beta 3 |
| Gene ID: |
2784 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
A single-nucleotide polymorphism (C825T) in this gene is associated with essential hypertension and obesity and is also associated with the occurrence of the splice variant GNB3-s, Beta subunits are required for GTPase activity, GNB3 encodes a beta subunit, There are families of related genes for each subunit, alpha, beta and gamma and are involved in the modulation and transduction of various transmembrane signalling systems, for replacement of GDP by GTP, regulate alpha subunits and for G protein-effector interactions, which appears to have increased activity, G proteins are composed of 3 units |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Also known as: |
G protein beta 3/GNB3 Antibody |
| Other name: |
Anti-G protein beta 3/GNB3 |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
G protein beta 3/GNB3 |
| Short name: |
Fluor 594, Anti-G protein beta 3/GNB3 |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-G protein b 3/GNB3 |
| Identity: |
4400 |
| Gene: |
GNB3 |
More about : GNB3 |
| Long gene name: |
G protein subunit beta 3 |
| Synonyms gene name: |
beta polypeptide 3 , guanine nucleotide binding protein (G protein) |
| Synonyms name: |
transducin beta chain 3 |
| Locus: |
12p13, 31 |
| Discovery year: |
1989-05-30 |
| Entrez gene record: |
2784 |
| Pubmed identfication: |
11770079 16600389 |
| RefSeq identity: |
NM_002075 |
| Classification: |
WD repeat domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000168517 |