| Long name: |
FITC Conjugated, G protein beta 3/GNB3 Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
G protein beta 3/GNB3 |
| Specificity: |
This is a highly specific antibody against G protein beta 3/GNB3 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human G protein beta 3 |
| Gene ID number: |
2784 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
A single-nucleotide polymorphism (C825T) in this gene is associated with essential hypertension and obesity and is also associated with the occurrence of the splice variant GNB3-s, Beta subunits are required for GTPase activity, GNB3 encodes a beta subunit, There are families of related genes for each subunit, alpha, beta and gamma and are involved in the modulation and transduction of various transmembrane signalling systems, for replacement of GDP by GTP, regulate alpha subunits and for G protein-effector interactions, which appears to have increased activity, G proteins are composed of 3 units |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
G protein beta 3/GNB3 Conjugated |
| Short name: |
FITC Conjugated, G protein beta 3/GNB3 Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, G protein b 3/GNB3 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
4400 |
| Gene: |
GNB3 |
More about : GNB3 |
| Long gene name: |
G protein subunit beta 3 |
| Synonyms gene name: |
beta polypeptide 3 , guanine nucleotide binding protein (G protein) |
| Synonyms name: |
transducin beta chain 3 |
| Locus: |
12p13, 31 |
| Discovery year: |
1989-05-30 |
| Entrez gene record: |
2784 |
| Pubmed identfication: |
11770079 16600389 |
| RefSeq identity: |
NM_002075 |
| Classification: |
WD repeat domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000168517 |