| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
NOX2/gp91phox |
| Specificity: |
This antibody reacts specifically with NOX2/gp91phox |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Cytoplasm |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human NOX2/gp91phox |
| Gene ID: |
1536 |
| Swiss Prot: |
P04839 |
| Applications: |
IF(ICC), IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(ICC)(1:50-200), IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Also functions as a voltage-gated proton channel that mediates the H(+) currents of resting phagocytes, It is the terminal component of a respiratory chain that transfers single electrons from cytoplasmic NADPH across the plasma membrane to molecular oxygen on the exterior, It participates in the regulation of cellular pH and is blocked by zinc, Critical component of the membrane-bound oxidase of phagocytes that generates superoxide |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
GP91-PHOX NOX2 |
| Also known as: |
NOX2/gp91phox Polyclonal Antibody |
| Other name: |
Anti-NOX2/gp91phox Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
NOX2/gp91phox |
| Short name: |
Anti-NOX2/gp91phox (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-NOX2/gp91phox (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
2578 |
| Gene: |
CYBB |
More about : CYBB |
| Long gene name: |
cytochrome b-245 beta chain |
| Synonyms gene: |
CGD |
| Synonyms gene name: |
beta polypeptide , chronic granulomatous disease cytochrome b-245 |
| Locus: |
Xp21, 1-p11, 4 |
| Discovery year: |
1986-01-01 |
| GenBank acession: |
X04011 |
| Entrez gene record: |
1536 |
| Havana BLAST/BLAT: |
OTTHUMG00000033175 |
| Locus Specific Databases: |
CYBBbase: Mutation registry for X-linked chronic granulomatous disease (previously known as X-CDGbase) LRG_53 |