NOX2 Antibody

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Catalog number: R30752
Price: 667 €
Supplier: genways
Product name: NOX2 Antibody
Quantity: 1 vial
Other quantities: 0.1mg 406€ 0.1ml 354€ 1000ug 801€
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More details :

Category: Antibody
Concentration: 2ml sterile DI water, 5mg/ml if reconstituted with 0
Form: Antigen affinity purified
Conjugation: Unconjugated
Clone: Polyclonal antibody
Recognised antigen: NOX2
Host animal: Rabbit (Oryctolagus cuniculus)
Clonality: Polyclonal (rabbit origin)
Species reactivity: Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications: IHC-P, WB
Recommended dilutions: 5-1ug/ml, 5-1ug/ml, IHC (Paraffin): 0, Western blot: 0
Notes: Titration of the NOX2 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts
Intented use: This NOX2 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #: P04839
Purity: Antigen affinity
Description: As a major player in innate immune responses in neutrophils, In heart cells, NOX2 assembled on DC phagosomes in a gp91-phox subunit-dependent manner, a membrane-bound enzyme complex that generates large quantities of microbicidal superoxide and other oxidants upon activation, also called p91-PHOX or GP91-1, and reactive oxygen species were produced in a more sustained manner in immature DC phagosomes than in macrophage phagosomes, is an essential component of phagocytic NADPH-oxidase, it is also involved in adaptive immunity through its activity in DCs, physiologic stretch rapidly activates reduced-form NOX2 to produce reactive oxygen species (ROS) in a process dependent on microtubules (X-ROS signaling), NADPH Oxidase 2
Immunogen: mouse and rat), An amino acid sequence from the middle region of human NOX2 (YWLCRDTHAFEWFADLLQ) was used as the immunogen for this NOX2 antibody (100% homologous in human
Storage: Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the NOX2 antibody can be stored for up to one month at 4oC, After reconstitution
Properties: C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene target: NOX2
Short name: NOX2 Antibody
Technique: antibodies against human proteins, antibodies for, Antibody
Alternative name: NOX2 (Antibody to)
Alternative technique: antibodies
Identity: 2578
Gene: CYBB | More about : CYBB
Long gene name: cytochrome b-245 beta chain
Synonyms gene: CGD
Synonyms gene name: beta polypeptide , chronic granulomatous disease cytochrome b-245
Synonyms: GP91-PHOX NOX2
Locus: Xp21, 1-p11, 4
Discovery year: 1986-01-01
GenBank acession: X04011
Entrez gene record: 1536
Havana BLAST/BLAT: OTTHUMG00000033175
Locus Specific Databases: CYBBbase: Mutation registry for X-linked chronic granulomatous disease (previously known as X-CDGbase) LRG_53

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