| Catalog number: | R30752 |
|---|---|
| Price: | 667 € |
| Supplier: | genways |
| Product name: | NOX2 Antibody |
| Quantity: | 1 vial |
| Other quantities: | 0.1mg 406€ 0.1ml 354€ 1000ug 801€ |
| Related search: |
| Category: | Antibody |
|---|---|
| Concentration: | 2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: | Antigen affinity purified |
| Conjugation: | Unconjugated |
| Clone: | Polyclonal antibody |
| Recognised antigen: | NOX2 |
| Host animal: | Rabbit (Oryctolagus cuniculus) |
| Clonality: | Polyclonal (rabbit origin) |
| Species reactivity: | Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: | IHC-P, WB |
| Recommended dilutions: | 5-1ug/ml, 5-1ug/ml, IHC (Paraffin): 0, Western blot: 0 |
| Notes: | Titration of the NOX2 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: | This NOX2 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: | P04839 |
| Purity: | Antigen affinity |
| Description: | As a major player in innate immune responses in neutrophils, In heart cells, NOX2 assembled on DC phagosomes in a gp91-phox subunit-dependent manner, a membrane-bound enzyme complex that generates large quantities of microbicidal superoxide and other oxidants upon activation, also called p91-PHOX or GP91-1, and reactive oxygen species were produced in a more sustained manner in immature DC phagosomes than in macrophage phagosomes, is an essential component of phagocytic NADPH-oxidase, it is also involved in adaptive immunity through its activity in DCs, physiologic stretch rapidly activates reduced-form NOX2 to produce reactive oxygen species (ROS) in a process dependent on microtubules (X-ROS signaling), NADPH Oxidase 2 |
| Immunogen: | mouse and rat), An amino acid sequence from the middle region of human NOX2 (YWLCRDTHAFEWFADLLQ) was used as the immunogen for this NOX2 antibody (100% homologous in human |
| Storage: | Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the NOX2 antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: | NOX2 |
| Short name: | NOX2 Antibody |
| Technique: | antibodies against human proteins, antibodies for, Antibody |
| Alternative name: | NOX2 (Antibody to) |
| Alternative technique: | antibodies |
| Identity: | 2578 |
| Gene: | CYBB | More about : CYBB |
| Long gene name: | cytochrome b-245 beta chain |
| Synonyms gene: | CGD |
| Synonyms gene name: | beta polypeptide , chronic granulomatous disease cytochrome b-245 |
| Synonyms: | GP91-PHOX NOX2 |
| Locus: | Xp21, 1-p11, 4 |
| Discovery year: | 1986-01-01 |
| GenBank acession: | X04011 |
| Entrez gene record: | 1536 |
| Havana BLAST/BLAT: | OTTHUMG00000033175 |
| Locus Specific Databases: | CYBBbase: Mutation registry for X-linked chronic granulomatous disease (previously known as X-CDGbase) LRG_53 |
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