| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
PSD95 Tyr236 + Tyr240 |
| Specificity: |
This antibody reacts specifically with PSD95 (Tyr236 + Tyr240) |
| Modification: |
Phosphorylation |
| Modification site: |
Tyr236 + Tyr240 |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic phosphopeptide derived from human PSD95 around the phosphorylation site of Tyr236/Tyr240 |
| Gene ID: |
1742 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
It heteromultimerizes with DLG2, These two MAGUK proteins may interact at postsynaptic sites to form a multimeric scaffold for the clustering of receptors, This gene encodes a member of the membrane-associated guanylate kinase (MAGUK) family, With DLG2 it is recruited into the same NMDA receptor and potassium channel clusters, and associated signaling proteins, ion channels, may be involved in guanine nucleotide-mediated signal transduction pathway, postsynaptic density protein 95 is a molecular scaffolding protein that binds and clusters N-methyl-D-aspartate receptors at neuronal synapses |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
PSD-95 PSD95 SAP90 SAP-90 |
| Also known as: |
PSD95 (Tyr236 + Tyr240) Antibody |
| Other name: |
Anti-PSD95 (Tyr236 + Tyr240) |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
PSD95 (Tyr236 + Tyr240) |
| Short name: |
Anti-PSD95 (Tyr236 + Tyr240) Fluor 594 |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-PSD95 (Tyr236 and Tyr240) |
| Identity: |
2903 |
| Gene: |
DLG4 |
More about : DLG4 |
| Long gene name: |
discs large MAGUK scaffold protein 4 |
| Synonyms gene name: |
discs, large homolog 4 (Drosophila) discs large homolog 4 |
| Locus: |
17p13, 1 |
| Discovery year: |
1995-11-07 |
| GenBank acession: |
U83192 |
| Entrez gene record: |
1742 |
| Pubmed identfication: |
9286702 |
| RefSeq identity: |
NM_001365 |
| Classification: |
Membrane associated guanylate kinases PDZ domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000134327 |