| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
MKP1 Ser359 |
| Specificity: |
This antibody reacts specifically with MKP1 (Ser359) |
| Modification: |
Phosphorylation |
| Modification site: |
Ser359 |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic phosphopeptide derived from human MKP1 around the phosphorylation site of Ser359 |
| Gene ID: |
1843 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
It specifies a protein with structural features similar to members of the non-receptor-type protein-tyrosine phosphatase family, The bacterially expressed and purified DUSP1 protein has intrinsic phosphatase activity, and specifically inactivates mitogen-activated protein (MAP) kinase in vitro by the concomitant dephosphorylation of both its phosphothreonine and phosphotyrosine residues, and which has significant amino-acid sequence similarity to a Tyr/Ser-protein phosphatase encoded by the late gene H1 of vaccinia virus, The expression of DUSP1 gene is induced in human skin fibroblasts by oxidative/heat stress and growth factors |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
3ch134, CL 100, CL100, DUSP 1, Dual Specicity Phosphatase 1, Dual specicity protein phosphatase 1, Dual specicity protein phosphatase hVH1, EC 3, EC 3, HVH 1, HVH1, MAP kinase phosphatase 1, MKP 1, MKP-1, MKP1, Mkp1, PTPN 10, PTPN10, Protein tyrosine phosphatase CL100, Ptpn16, Serine/threonine specic protein phosphatase, VH 1, VH1, 1, 1, 3, 3, 16, 48, Mitogen activated protein kinase phosphatase 1 |
| Also known as: |
MKP1 (Ser359) Polyclonal Antibody |
| Other name: |
Anti-MKP1 (Ser359) Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
MKP1 (Ser359) |
| Short name: |
Anti-MKP1 (Ser359) (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-MKP1 (Ser359) (polyclonal) |
| Alternative technique: |
polyclonals |