| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
DUSP1/MKP1 |
| Specificity: |
This antibody may interact with DUSP4/MKP2DUSP1/MKP1 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Nucleus |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human DUSP1 |
| Gene ID: |
1843 |
| Swiss Prot: |
P28562 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
regulating its activity during the meiotic cell cycle, Dual specificity phosphatase that dephosphorylates MAP kinase MAPK1/ERK2 on both 'Thr-183' and 'Tyr-185' |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
YVH1 DUSP1 |
| Also known as: |
DUSP1/MKP1 Polyclonal Antibody |
| Other name: |
Anti-DUSP1/MKP1 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
DUSP1/MKP1 |
| Short name: |
Anti-DUSP1/MKP1 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-dual specificity phosphatase 1/MKP1 (polyclonal) |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
BT, CL100 and HVH1 and MKP-1 and MKP1 and PTPN10, DUSP1 and IDBG-57812 and ENSG00000120129 and 1843, Dusp1 and IDBG-155234 and ENSMUSG00000024190 and 19252, MAP kinase tyrosine/serine/threonine phosphatase activity, nuclei, this GO :0000188 and inactivation of MAPK activity and biological process this GO :0001706 and endoderm formation and biological process this GO :0004725 and protein tyrosine phosphatase activity and molecular function this GO :0004726 and non-membrane spanning protein tyrosine phosphatase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0006470 and protein dephosphorylation and biological process this GO :0006979 and response to oxidative stress and biological process this GO :0008138 and protein tyrosine/serine/threonine phosphatase activity and molecular function this GO :0008330 and protein tyrosine/threonine phosphatase activity and molecular function this GO :0009416 and response to light stimulus and biological process this GO :0010033 and response to organic substance and biological process this GO :0016311 and dephosphorylation and biological process this GO :0016791 and phosphatase activity and molecular function this GO :0017017 and MAP kinase tyrosine/serine/threonine phosphatase activity and molecular function this GO :0032355 and response to estradiol and biological process this GO :0032526 and response to retinoic acid and biological process this GO :0032870 and cellular response to hormone stimulus and biological process this GO :0033574 and response to testosterone and biological process this GO :0035335 and peptidyl-tyrosine dephosphorylation and biological process this GO :0035556 and intracellular signal transduction and biological process this GO :0035970 and peptidyl-threonine dephosphorylation and biological process this GO :0042542 and response to hydrogen peroxide and biological process this GO :0042981 and regulation of apoptotic process and biological process this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043407 and negative regulation of MAP kinase activity and biological process this GO :0043409 and negative regulation of MAPK cascade and biological process this GO :0045087 and innate immune response and biological process this GO :0051384 and response to glucocorticoid and biological process this GO :0051447 and negative regulation of meiotic cell cycle and biological process this GO :0051591 and response to cAMP and biological process this GO :0051592 and response to calcium ion and biological process this GO :0070373 and negative regulation of ERK1 and ERK2 cascade and biological process this GO :0071850 and mitotic cell cycle arrest and biological process this GO :0090266 and regulation of mitotic cell cycle spindle assembly checkpoint and biological process this GO :2000279 and negative regulation of DNA biosynthetic process and biological process, this GO :0004725 : protein tyrosine phosphatase activity, this GO :0004725 : protein tyrosine phosphatase activity and also this GO :0004726 : non-membrane spanning protein tyrosine phosphatase activity and also this GO :0005515 : protein binding and also this GO :0008138 : protein tyrosine/serine/threonine phosphatase activity and also this GO :0008330 : protein tyrosine/threonine phosphatase activity and also this GO :0016791 : phosphatase activity and also this GO :0017017 : MAP kinase tyrosine/serine/threonine phosphatase activity, this GO :0004726 : non-membrane spanning protein tyrosine phosphatase activity, this GO :0005515 : protein binding, this GO :0008138 : protein tyrosine/serine/threonine phosphatase activity, this GO :0008330 : protein tyrosine/threonine phosphatase activity, this GO :0016791 : phosphatase activity, this GO :0017017 : MAP kinase tyrosine/serine/threonine phosphatase activity, 85182 and IDBG-628495 and ENSBTAG00000013863 and 539175, dual specificity phosphatase 1 |
| Identity: |
3067 |
| Gene: |
DUSP12 |
More about : DUSP12 |
| Long gene name: |
dual specificity phosphatase 12 |
| Synonyms name: |
cerevisiae) ortholog , serine/threonine specific protein phosphatase YVH1 protein-tyrosine phosphatase (S |
| Locus: |
1q23, 3 |
| Discovery year: |
2000-01-31 |
| GenBank acession: |
AF119226 |
| Entrez gene record: |
11266 |
| Pubmed identfication: |
10446167 |
| RefSeq identity: |
NM_007240 |
| Classification: |
Atypical dual specificity phosphatases |
| Havana BLAST/BLAT: |
OTTHUMG00000034540 |