| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
MEK6 Ser207 |
| Specificity: |
This antibody reacts specifically with MEK6 (Ser207) |
| Modification: |
Phosphorylation |
| Modification site: |
Ser207 |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic phosphopeptide derived from human MEK6 around the phosphorylation site of Ser207 |
| Gene ID: |
5608 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
MEK6, MKK or MEKs), catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in MAP kinase p38, closely related to MEK3, in response to inflammatory cytokines and environmental stress, this protein is involved in many cellular processes such as stress induced cell cycle arrest, thus activating it, transcription activation and apoptosis, As an essential component of p38 MAP kinase mediated signal transduction pathway, Mitogen activated protein kinase kinase 6 (MEK6 or MKK6) belongs to the serine/threonine protein kinase family and the MAPK kinase subfamily (MAP2K |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
MEK6 MKK6 SAPKK3 MAPKK6 |
| Also known as: |
MEK6 (Ser207) Polyclonal Antibody |
| Other name: |
Anti-MEK6 (Ser207) Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
MEK6 (Ser207) |
| Short name: |
Anti-MEK6 (Ser207) (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-MEK6 (Ser207) (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
6846 |
| Gene: |
MAP2K6 |
More about : MAP2K6 |
| Long gene name: |
mitogen-activated protein kinase kinase 6 |
| Synonyms gene: |
PRKMK6 |
| Synonyms name: |
kinase 6 (MAP kinase kinase 6) , mitogen-activated, protein kinase |
| Locus: |
17q24, 3 |
| Discovery year: |
1997-11-11 |
| GenBank acession: |
U39064 |
| Entrez gene record: |
5608 |
| Pubmed identfication: |
8621675 |
| RefSeq identity: |
NM_002758 |
| Classification: |
Mitogen-activated protein kinase kinases |
| Havana BLAST/BLAT: |
OTTHUMG00000180311 |