| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
Ephrin B Tyr324 + Tyr329 |
| Specificity: |
Ephrin B (Tyr324 + Tyr329), These phosphorylation sites are homologous to Tyr323 + Tyr328 in Mouse |
| Modification: |
Phosphorylation |
| Modification site: |
Tyr324 + Tyr329 |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Cell membrane, Cytoplasm |
| Antigen Source: |
KLH conjugated synthetic phosphopeptide derived from human Ephrin B around the phosphorylation site of Tyr324/329 |
| Gene ID: |
1947 |
| Swiss Prot: |
P98172 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Binds promiscuously Eph receptors residing on adjacent cells, Binds to, Binds to, Binds to the receptor tyrosine kinases EPHB3 (preferred), Cell surface transmembrane ligand for Eph receptors, EPHB1 and EPHA1, May play a role in constraining the orientation of longitudinally projecting axons (By similarity), May play a role in constraining the orientation of longitudinally projecting axons (By similarity), The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling, a family of receptor tyrosine kinases which are crucial for migration, and induce the collapse of, and induce the collapse of, commissural axons/growth cones in vitro, commissural axons/growth cones in vitro, leading to contact-dependent bidirectional signaling into neighboring cells, repulsion and adhesion during neuronal, vascular and epithelial development, Binds to the receptor tyrosine kinases EPHB1 and EPHA1 |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
CFNS, EFB1, EFL-3, EFL3, EFNB1, ELK ligand, EPH-related receptor tyrosine kinase ligand 2, EPLG2, Elk-L, Ephrin-B1, LERK-2, LERK2, CFND |
| Also known as: |
Ephrin B (Tyr324 + Tyr329) Antibody |
| Other name: |
Anti-Ephrin B (Tyr324 + Tyr329) |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
Ephrin B (Tyr324 + Tyr329) |
| Short name: |
Anti-Ephrin B (Tyr324 + Tyr329) Fluor 594 |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-Ephrin B (Tyr324 and Tyr329) |