Anti-CBL2 (Tyr774) (Polyclonal), ALEXA Fluor 594

Catalog number:	GENTAUR-58be61459b66d Buy Now
Price:	350 €
Supplier:	Bioss Primary Conjugated Antibodies.
Product name:	Anti-CBL2 (Tyr774) (Polyclonal), ALEXA Fluor 594
Quantity:	100ul
Related search:	cbl gene polyclonal antibody protein synonyms nbsp degradation

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Type:	Conjugated Primary Antibody
Conjugated with:	594, ALEXA FLUOR®
Host organism:	Rabbit (Oryctolagus cuniculus)
Target Protein/Peptide:	CBL2 Tyr774
Specificity:	This antibody reacts specifically with CBL2 (Tyr774)
Modification:	Phosphorylation
Modification site:	Tyr774
Clonality:	Polyclonal Antibody
Clone:	Polyclonal Antibodies
Concentration:	1ug per 1ul
Antigen Source:	KLH conjugated synthetic phosphopeptide derived from human CBL2 around the phosphorylation site of Tyr774
Gene ID:	867
Applications:	IF(IHC-P)
Applications with corresponding dilutions:	IF(IHC-P)(1:50-200)
Cross reactive species:	Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details:	However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information:	As such it functions as a negative regulator of many signal transduction pathways, Mar 2012], Mutations in this gene are also the cause of Noonan syndrome-like disorder, The encoded protein is one of the enzymes required for targeting substrates for degradation by the proteasome, This gene has been found to be mutated or translocated in many cancers including acute myeloid leukaemia, This protein also contains an N-terminal phosphotyrosine binding domain that allows it to interact with numerous tyrosine-phosphorylated substrates and target them for proteasome degradation, This protein mediates the transfer of ubiquitin from ubiquitin conjugating enzymes (E2) to specific substrates, [provided by RefSeq, This gene is a proto-oncogene that encodes a RING finger E3 ubiquitin ligase
Purification method:	Purified by Protein A
Storage:	50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission:	590nm/617nm
Synonyms:	RNF55 c-Cbl
Also known as:	CBL2 (Tyr774) Polyclonal Antibody
Other name:	Anti-CBL2 (Tyr774) Polyclonal
Advisory:	For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
Properties:	For facs or microscopy Alexa 1 conjugate
Conjugation:	Alexa Fluor
Group:	Polyclonals and antibodies
About:	The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene target:	CBL2 (Tyr774)
Short name:	Anti-CBL2 (Tyr774) (Polyclonal) Fluor 594
Technique:	Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different
Label:	ALEXA
Alternative name:	ALEXA Fluor 594, antibody to-CBL2 (Tyr774) (polyclonal)
Alternative technique:	polyclonals
Identity:	1541
Gene:	CBL | More about : CBL
Long gene name:	Cbl proto-oncogene
Synonyms gene:	CBL2
Synonyms gene name:	Cas-Br-M (murine) ecotropic retroviral transforming sequence Cbl proto-oncogene, E3 ubiquitin protein ligase
Synonyms name:	oncogene CBL2
Locus:	11q23, 3
Discovery year:	1989-06-30
GenBank acession:	X57110
Entrez gene record:	867
Pubmed identfication:	2013228
RefSeq identity:	NM_005188
Classification:	Ring finger proteins
Havana BLAST/BLAT:	OTTHUMG00000166170
Locus Specific Databases:	LRG_608

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