| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
CENPA Ser7 |
| Specificity: |
This antibody reacts specifically with CENPA (Ser7) |
| Modification: |
Phosphorylation |
| Modification site: |
Ser7 |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic phosphopeptide derived from human CENP-A around the phosphorylation site of Ser7 [RR(p-S)RK] |
| Gene ID: |
1058 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Alternative splicing results in multiple transcript variants encoding distinct isoforms, CENPA encodes a centromere protein which contains a histone H3 related histone fold domain that is required for targeting to the centromere, CENPA is proposed to be a component of a modified nucleosome or nucleosome-like structure in which it replaces 1 or both copies of conventional histone H3 in the (H3-H4)2 tetrameric core of the nucleosome particle, [provided by RefSeq], Centromeres are the differentiated chromosomal domains that specify the mitotic behavior of chromosomes |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
CENP-A CenH3 |
| Also known as: |
CENPA (Ser7) Polyclonal Antibody |
| Other name: |
Anti-CENPA (Ser7) Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
CENPA (Ser7) |
| Short name: |
Anti-CENPA (Ser7) (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-CENPA (Ser7) (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
1851 |
| Gene: |
CENPA |
More about : CENPA |
| Long gene name: |
centromere protein A |
| Synonyms gene name: |
17kDa , centromere protein A (17kD) centromere protein A |
| Synonyms name: |
centromere-specific histone histone H3-like centromeric protein A |
| Locus: |
2p23, 3 |
| Discovery year: |
1988-05-31 |
| GenBank acession: |
U14518 |
| Entrez gene record: |
1058 |
| RefSeq identity: |
NM_001809 |
| Havana BLAST/BLAT: |
OTTHUMG00000097073 |