| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
HAS1 |
| Specificity: |
This antibody reacts specifically with HAS1 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Extracellular |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human Hyaluronan synthase 1 |
| Gene ID: |
3036 |
| Swiss Prot: |
Q92839 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Also able to catalyze the synthesis of chito-oligosaccharide depending on the substrate (By similarity), Therefore, This is one of the isozymes catalyzing that reaction, it is essential to hyaluronan synthesis a major component of most extracellular matrices that has a structural role in tissues architectures and regulates cell adhesion, migration and differentiation, Catalyzes the addition of GlcNAc or GlcUA monosaccharides to the nascent hyaluronan polymer |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Also known as: |
HAS1 Polyclonal Antibody |
| Other name: |
Anti-HAS1 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
HAS1 |
| Short name: |
Anti-HAS1 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-hyaluronan synthase 1 (polyclonal) |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
HAS, HAS1 and IDBG-641414 and ENSBTAG00000017672 and 101907856, HAS1 and IDBG-66243 and ENSG00000105509 and 3036, Has1 and IDBG-141052 and ENSMUSG00000003665 and 15116, Plasma membranes, hyaluronan synthase activity, this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0005975 and carbohydrate metabolic process and biological process this GO :0006024 and glycosaminoglycan biosynthetic process and biological process this GO :0007155 and cell adhesion and biological process this GO :0010764 and negative regulation of fibroblast migration and biological process this GO :0016020 and membrane and cellular component this GO :0030203 and glycosaminoglycan metabolic process and biological process this GO :0030212 and hyaluronan metabolic process and biological process this GO :0030213 and hyaluronan biosynthetic process and biological process this GO :0036120 and cellular response to platelet-derived growth factor stimulus and biological process this GO :0044281 and small molecule metabolic process and biological process this GO :0045226 and extracellular polysaccharide biosynthetic process and biological process this GO :0050501 and hyaluronan synthase activity and molecular function this GO :0085029 and extracellular matrix assembly and biological process, this GO :0050501 : hyaluronan synthase activity, this GO :0050501 : hyaluronan synthase activity, 282820, hyaluronan synthase 1 |
| Identity: |
4818 |
| Gene: |
HAS1 |
More about : HAS1 |
| Long gene name: |
hyaluronan synthase 1 |
| Synonyms gene: |
HAS |
| Locus: |
19q13, 41 |
| Discovery year: |
1996-04-12 |
| GenBank acession: |
U59269 |
| Entrez gene record: |
3036 |
| Pubmed identfication: |
9169154 |
| RefSeq identity: |
NM_001523 |
| Classification: |
Glycosyltransferase family 2 |
| Havana BLAST/BLAT: |
OTTHUMG00000183499 |