| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
CLEC5A |
| Specificity: |
This antibody reacts specifically with CLEC5A |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Extracellular |
| Antigen Source: |
KLH conjugated synthetic peptide derived from mouse CLEC5A |
| Gene ID: |
23845 |
| Swiss Prot: |
Q9R007 |
| Applications: |
IF(IHC-P), FCM |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Acts as a key regulator of synovial injury and bone erosion during autoimmune joint inflammation, Cell surface receptor that signals via TYROBP, Critical macrophage receptor for dengue virus serotypes 1-4, Regulates inflammatory responses, The binding of dengue virus to CLEC5A triggers signaling through phosphylation of TYROBP, this interaction does not result in viral entry but stimulates proinflammatory cytokine release, Functions as a positive regulator of osteoclastogenesis |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
MDL-1 |
| Also known as: |
CLEC5A Polyclonal Antibody |
| Other name: |
Anti-CLEC5A Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
CLEC5A |
| Short name: |
Anti-CLEC5A (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, member A (polyclonal), antibody to-C-classification lectin domain family 5 |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
CLEC5A and IDBG-546985 and ENSG00000258227 and 23601, CLEC5A and IDBG-636542 and ENSBTAG00000020453 and 615201, CLECSF5 and MDL-1 and MDL1, Cell surfaces, Clec5a and IDBG-139294 and ENSMUSG00000029915 and 23845, carbohydrate binding, member A, this GO :0001618 and virus receptor activity and molecular function this GO :0002076 and osteoblast development and biological process this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006968 and cellular defense response and biological process this GO :0007165 and signal transduction and biological process this GO :0009615 and response to virus and biological process this GO :0009986 and cell surface and cellular component this GO :0016032 and viral process and biological process this GO :0030246 and carbohydrate binding and molecular function this GO :0033033 and negative regulation of myeloid cell apoptotic process and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0045087 and innate immune response and biological process this GO :0050715 and positive regulation of cytokine secretion and biological process, this GO :0001618 : virus receptor activity, this GO :0001618 : virus receptor activity and also this GO :0005515 : protein binding and also this GO :0030246 : carbohydrate binding, this GO :0005515 : protein binding, this GO :0030246 : carbohydrate binding, C-type lectin domain family 5 |
| Identity: |
2054 |
| Gene: |
CLEC5A |
More about : CLEC5A |
| Long gene name: |
C-type lectin domain family 5 member A |
| Synonyms gene: |
CLECSF5 |
| Synonyms gene name: |
C-type (calcium dependent, carbohydrate-recognition domain) lectin, member A , superfamily member 5 C-type lectin domain family 5 |
| Locus: |
7q34 |
| Discovery year: |
1999-10-19 |
| Entrez gene record: |
23601 |
| Pubmed identfication: |
10449773 |
| RefSeq identity: |
NM_013252 |
| Classification: |
C-type lectin domain family |
| Havana BLAST/BLAT: |
OTTHUMG00000157173 |