| Long name: |
FITC Conjugated, CLEC5A Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
CLEC5A |
| Specificity: |
This is a highly specific antibody against CLEC5A |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
90-130/190 |
| Subcellular location: |
Extracellular |
| Source: |
KLH conjugated synthetic peptide derived from mouse CLEC5A |
| Gene ID number: |
23845 |
| Swiss Prot: |
Q9R007 |
| Tested applications: |
IF(IHC-P), FCM |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Acts as a key regulator of synovial injury and bone erosion during autoimmune joint inflammation, Cell surface receptor that signals via TYROBP, Critical macrophage receptor for dengue virus serotypes 1-4, Regulates inflammatory responses, The binding of dengue virus to CLEC5A triggers signaling through phosphylation of TYROBP, this interaction does not result in viral entry but stimulates proinflammatory cytokine release, Functions as a positive regulator of osteoclastogenesis |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
MDL-1 |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
CLEC5A Conjugated |
| Short name: |
FITC Conjugated, CLEC5A Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, member A (Antibody to), C-classification lectin domain family 5 |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
CLEC5A and IDBG-546985 and ENSG00000258227 and 23601, CLEC5A and IDBG-636542 and ENSBTAG00000020453 and 615201, CLECSF5 and MDL-1 and MDL1, Cell surfaces, Clec5a and IDBG-139294 and ENSMUSG00000029915 and 23845, carbohydrate binding, member A, this GO :0001618 and virus receptor activity and molecular function this GO :0002076 and osteoblast development and biological process this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006968 and cellular defense response and biological process this GO :0007165 and signal transduction and biological process this GO :0009615 and response to virus and biological process this GO :0009986 and cell surface and cellular component this GO :0016032 and viral process and biological process this GO :0030246 and carbohydrate binding and molecular function this GO :0033033 and negative regulation of myeloid cell apoptotic process and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0045087 and innate immune response and biological process this GO :0050715 and positive regulation of cytokine secretion and biological process, this GO :0001618 : virus receptor activity, this GO :0001618 : virus receptor activity and also this GO :0005515 : protein binding and also this GO :0030246 : carbohydrate binding, this GO :0005515 : protein binding, this GO :0030246 : carbohydrate binding, C-type lectin domain family 5 |
| Identity: |
2054 |
| Gene: |
CLEC5A |
More about : CLEC5A |
| Long gene name: |
C-type lectin domain family 5 member A |
| Synonyms gene: |
CLECSF5 |
| Synonyms gene name: |
C-type (calcium dependent, carbohydrate-recognition domain) lectin, member A , superfamily member 5 C-type lectin domain family 5 |
| Locus: |
7q34 |
| Discovery year: |
1999-10-19 |
| Entrez gene record: |
23601 |
| Pubmed identfication: |
10449773 |
| RefSeq identity: |
NM_013252 |
| Classification: |
C-type lectin domain family |
| Havana BLAST/BLAT: |
OTTHUMG00000157173 |