| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
STAT4 |
| Specificity: |
This antibody reacts specifically with STAT4 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human STAT4 |
| Gene ID: |
6775 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Alternate splicing results in multiple transcript variants that encode the same protein, Aug 2011], In response to cytokines and growth factors, Mutations in this gene may be associated with systemic lupus erythematosus and rheumatoid arthritis, STAT family members are phosphorylated by the receptor associated kinases, This protein is essential for mediating responses to IL12 in lymphocytes, [provided by RefSeq, and regulating the differentiation of T helper cells, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators, The protein encoded by this gene is a member of the STAT family of transcription factors |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Also known as: |
STAT4 Polyclonal Antibody |
| Other name: |
Anti-STAT4 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
STAT4 |
| Short name: |
Anti-STAT4 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-signal transducer and activator on transcription 4 (polyclonal) |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
DNA-templated and biological process this GO :0006355 and regulation of transcription, DNA-templated and biological process this GO :0006468 and protein phosphorylation and biological process this GO :0007165 and signal transduction and biological process this GO :0007259 and JAK-STAT cascade and biological process this GO :0008283 and cell proliferation and biological process this GO :0019221 and cytokine-mediated signaling pathway and biological process this GO :0043565 and sequence-specific DNA binding and molecular function this GO :0045087 and innate immune response and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0071310 and cellular response to organic substance and biological process, SLEB11, STAT4 and IDBG-642767 and ENSBTAG00000046699 and, STAT4 and IDBG-77625 and ENSG00000138378 and 6775, Stat4 and IDBG-152917 and ENSMUSG00000062939 and 20849, nuclei, sequence-specific DNA binding, this GO :0003677 and DNA binding and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0004871 and signal transducer activity and molecular function this GO :0005509 and calcium ion binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0006351 and transcription, this GO :0003677 : DNA binding, this GO :0003677 : DNA binding and also this GO :0003700 : sequence-specific DNA binding transcription factor activity and also this GO :0004871 : signal transducer activity and also this GO :0005509 : calcium ion binding and also this GO :0043565 : sequence-specific DNA binding, this GO :0003700 : sequence-specific DNA binding transcription factor activity, this GO :0004871 : signal transducer activity, this GO :0005509 : calcium ion binding, this GO :0043565 : sequence-specific DNA binding, signal transducer and activator of transcription 4 |
| Identity: |
11365 |
| Gene: |
STAT4 |
More about : STAT4 |
| Long gene name: |
signal transducer and activator of transcription 4 |
| Locus: |
2q32, 2-q32, 3 |
| Discovery year: |
1995-11-08 |
| Entrez gene record: |
6775 |
| Pubmed identfication: |
8007943 8700208 |
| RefSeq identity: |
NM_003151 |
| Classification: |
SH2 domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000132700 |