| known also as: |
Anti-RABBIT ANTI MOUSE STAT4 |
| known also as: |
RABBIT ANTI Murine STAT4 |
| known also as: |
Lapin ANTI Mus musculus STAT4 |
| known also as: |
STAT4 |
| Other names: |
N/A, Signal transducer and activator of transcription 4, signal transducer and activator of transcription 4, signal transducer and activator of transcription 4, signal transducer and activator of transcription 4 |
| Gene name: |
STAT4 |
| Other gene names: |
N/A, N/A, Stat4, Stat4 |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Immunoglobulin isotype: |
Polyclonal IgG |
| Clone: |
Polyclonal antibody |
| Host organism: |
Rabbit |
| Species reactivity: |
Mouse |
| Specificity and cross-reactivity: |
Here STAT4 can bind DNA and directly activate cytokine target genes, These in turn phosphorylate and activate STAT4, _x000D__x000D_STAT4 is activated in response to cytokine cell signalling, _x000D__x000D_Stat4 expression is restricted to myeloid cells, a transcription factor which is essential for mediating responses to interleukin-12 (IL-12) in lymphocytes, and an isoform lacking the C-terminal amino-acids that comprise the transactivation domain (STAT4?), and for the function and development of T helper cells, and translocates to the nucleus, full length STAT4 (STAT4?), thymus and testis, where it exists in two forms, which first activates the kinases Tyk2 and Jak2, which forms homo- or heterodimers with other STAT proteins, STAT4 This item recognises mouse STAT4 |
| Form/Appearance: |
Serum (Serum - liquid) |
| Storage and shipping: |
Avoid repeated freezing and thawing as this may denature the antibody, Shelf Life: 18 months from date of dispatch, Should productone contain a precipitate we recommend microcentrifugation before use, Storage in frost-free freezers is not recommended, if preferred, or productone should be stored at -20 degrees Celsius, productone should be stored undiluted, Store at +Store productone at +4 degrees Celsius |
| Tested for:: |
ELISA (EIA), Western Blot (WB), Immunoprecipitation (IP) |
| Description: |
Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS Polyclonals_1 they should be stored frozen at - 24° |
| Gene target: |
STAT4 |
| Short name: |
Anti-MOUSE STAT4 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
antibody to-MOUSE signal transducer and activator on transcription 4 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
DNA-templated and biological process this GO :0006355 and regulation of transcription, DNA-templated and biological process this GO :0006468 and protein phosphorylation and biological process this GO :0007165 and signal transduction and biological process this GO :0007259 and JAK-STAT cascade and biological process this GO :0008283 and cell proliferation and biological process this GO :0019221 and cytokine-mediated signaling pathway and biological process this GO :0043565 and sequence-specific DNA binding and molecular function this GO :0045087 and innate immune response and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0071310 and cellular response to organic substance and biological process, SLEB11, STAT4 and IDBG-642767 and ENSBTAG00000046699 and, STAT4 and IDBG-77625 and ENSG00000138378 and 6775, Stat4 and IDBG-152917 and ENSMUSG00000062939 and 20849, nuclei, sequence-specific DNA binding, this GO :0003677 and DNA binding and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0004871 and signal transducer activity and molecular function this GO :0005509 and calcium ion binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0006351 and transcription, this GO :0003677 : DNA binding, this GO :0003677 : DNA binding and also this GO :0003700 : sequence-specific DNA binding transcription factor activity and also this GO :0004871 : signal transducer activity and also this GO :0005509 : calcium ion binding and also this GO :0043565 : sequence-specific DNA binding, this GO :0003700 : sequence-specific DNA binding transcription factor activity, this GO :0004871 : signal transducer activity, this GO :0005509 : calcium ion binding, this GO :0043565 : sequence-specific DNA binding, signal transducer and activator of transcription 4 |
| Identity: |
11365 |
| Gene: |
STAT4 |
More about : STAT4 |
| Long gene name: |
signal transducer and activator of transcription 4 |
| Locus: |
2q32, 2-q32, 3 |
| Discovery year: |
1995-11-08 |
| Entrez gene record: |
6775 |
| Pubmed identfication: |
8007943 8700208 |
| RefSeq identity: |
NM_003151 |
| Classification: |
SH2 domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000132700 |