| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
2, Kir6 |
| Specificity: |
2, This antibody reacts specifically with Kir6 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human Kir62 |
| Gene ID: |
3767 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Defects in this gene may also contribute to autosomal dominant non-insulin-dependent diabetes mellitus type II (NIDDM), Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene, Mutations in this gene are a cause of familial persistent hyperinsulinemic hypoglycemia of infancy (PHHI), The encoded protein, The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel, [provided by RefSeq], an autosomal recessive disorder characterized by unregulated insulin secretion, and permanent neonatal diabetes mellitus (PNDM), is controlled by G-proteins and is found associated with the sulfonylurea receptor SUR, transient neonatal diabetes mellitus type 3 (TNDM3), where they participate in a wide range of physiologic responses, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, Potassium channels are present in most mammalian cells |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
Kir6, 2 BIR |
| Also known as: |
2 Polyclonal Antibody, Kir6 |
| Other name: |
2 Polyclonal, Anti-Kir6 |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
2, Kir6 |
| Short name: |
2 (Polyclonal) Fluor 594, Anti-Kir6 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, 2 (polyclonal), antibody to-Kir6 |
| Alternative technique: |
polyclonals |
| Identity: |
6257 |
| Gene: |
KCNJ11 |
More about : KCNJ11 |
| Long gene name: |
potassium voltage-gated channel subfamily J member 11 |
| Synonyms gene name: |
member 11 , potassium inwardly-rectifying channel, subfamily J |
| Locus: |
11p15, 1 |
| Discovery year: |
1997-09-12 |
| GenBank acession: |
D50582 |
| Entrez gene record: |
3767 |
| Pubmed identfication: |
7502040 16382105 |
| RefSeq identity: |
NM_000525 |
| Classification: |
Potassium voltage-gated channel subfamily J |
| Havana BLAST/BLAT: |
OTTHUMG00000165914 |