| Long name: |
2 Primary Polyclonal Antibody, Kir6 |
| Also known as: |
2 PAb, Kir6 |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
2, Kir6 |
| Specificity: |
2, This is a highly specific antibody against Kir6 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Kir62 |
| Gene ID number: |
3767 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Defects in this gene may also contribute to autosomal dominant non-insulin-dependent diabetes mellitus type II (NIDDM), Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene, Mutations in this gene are a cause of familial persistent hyperinsulinemic hypoglycemia of infancy (PHHI), The encoded protein, The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel, [provided by RefSeq], an autosomal recessive disorder characterized by unregulated insulin secretion, and permanent neonatal diabetes mellitus (PNDM), is controlled by G-proteins and is found associated with the sulfonylurea receptor SUR, transient neonatal diabetes mellitus type 3 (TNDM3), where they participate in a wide range of physiologic responses, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, Potassium channels are present in most mammalian cells |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
BIR, Beta cell inward rectier subunit, HHF 2, HHF2, IKATP, IRK 11, IRK11, IRK11_HUMAN, Inward rectier K+ channel Kir6, Inwardly rectying potassium channel KIR6, KCNJ11, Kir 6, Kir6, MGC133230, PHHI, Potassium channel, Potassium inwardly rectying channel J11, TNDM 3, TNDM3, inwardly rectying subfamily J member 11, mBIR, 2, 2, 2, 2, ATP sensitive inward rectier potassium channel 11 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
2, Kir6 |
| Short name: |
2 Antibody, Kir6 |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
2 (Antibody to), Kir6 |
| Alternative technique: |
antibodies |
| Identity: |
6257 |
| Gene: |
KCNJ11 |
More about : KCNJ11 |
| Long gene name: |
potassium voltage-gated channel subfamily J member 11 |
| Synonyms gene name: |
member 11 , potassium inwardly-rectifying channel, subfamily J |
| Synonyms: |
Kir6, 2 BIR |
| Locus: |
11p15, 1 |
| Discovery year: |
1997-09-12 |
| GenBank acession: |
D50582 |
| Entrez gene record: |
3767 |
| Pubmed identfication: |
7502040 16382105 |
| RefSeq identity: |
NM_000525 |
| Classification: |
Potassium voltage-gated channel subfamily J |
| Havana BLAST/BLAT: |
OTTHUMG00000165914 |