Anti-Smad3 (Ser423) (Polyclonal), ALEXA Fluor 594

Catalog number:	GENTAUR-58be607761063 Buy Now
Price:	368 €
Supplier:	Bioss Primary Conjugated Antibodies
Product name:	Anti-Smad3 (Ser423) (Polyclonal), ALEXA Fluor 594
Quantity:	0.1ml
Related search:	smad ser polyclonal antibody beta tgf nbsp signaling

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Type:	Conjugated Primary Antibody
Conjugated with:	594, ALEXA FLUOR®
Host organism:	Rabbit (Oryctolagus cuniculus)
Target Protein/Peptide:	Smad3 Ser423
Specificity:	This antibody reacts specifically with Smad3 (Ser423)
Modification:	Phosphorylation
Modification site:	Ser423
Clonality:	Polyclonal Antibody
Clone:	Polyclonal Antibodies
Concentration:	1ug per 1ul
Antigen Source:	KLH conjugated synthetic phosphopeptide derived from human Smad3 around the phosphorylation site of Ser423
Gene ID:	4088
Applications:	IF(IHC-P)
Applications with corresponding dilutions:	IF(IHC-P)(1:50-200)
Cross reactive species:	Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details:	However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information:	(Smad4) that functions via its interaction to the various Smads, (Smad6 and 7), 5, Activated Smad3 oligomerizes with Smad4 upon TGF beta stimulation and translocates as a complex into the nucleus, Phosphorylation of the two TGF beta dependent serines 423 and 425 in the C terminus of Smad3 is critical for Smad3 transcriptional activity and TGF beta signaling, The Smad family is divided into three subclasses: receptor regulated Smads, activin/TGF beta receptor regulated (Smad2 and 3) or BMP receptor regulated (Smad 1, allowing its binding to DNA and transcription factors, and 8), and the inhibitory Smads, differentiation and development, the common partner, Smad3 is a 50 kDa member of a family of proteins that act as key mediators of TGF beta superfamily signaling in cell proliferation
Purification method:	Purified by Protein A
Storage:	50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission:	590nm/617nm
Synonyms:	HSPC193, JV15 2, JV152, MAD mothers against decapentaplegic Drosophila homolog 3, MAD3, MADH 3, MADH3, Mothers against DPP homolog 3, Mothers against decapentaplegic homolog 3, SMA and MAD related protein 3, SMAD, SMAD 3, SMAD-3, SMAD3_HUMAN, Smad3 phospho S423, hMAD 3, hSMAD3, p-Smad3 Ser423, Smad3 phospho Ser423
Also known as:	Smad3 (Ser423) Polyclonal Antibody
Other name:	Anti-Smad3 (Ser423) Polyclonal
Advisory:	For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
Properties:	For facs or microscopy Alexa 1 conjugate
Conjugation:	Alexa Fluor
Group:	Polyclonals and antibodies
About:	The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene target:	Smad3 (Ser423)
Short name:	Anti-Smad3 (Ser423) (Polyclonal) Fluor 594
Technique:	Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different
Label:	ALEXA
Alternative name:	ALEXA Fluor 594, antibody to-SMAD family member 3 (Ser423) (polyclonal)
Alternative technique:	polyclonals

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