| Type: |
Primary Antibody |
| Conjugated with: |
Unconjugated |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
SMYD2 |
| Specificity: |
This antibody reacts specifically with SMYD2 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Nucleus, Cytoplasm |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human SMYD2 |
| Gene ID: |
56950 |
| Swiss Prot: |
Q9NRG4 |
| Applications: |
IF(IHC-P), IHC-P |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Monomethylates 'Lys-370' of p53/TP53, Monomethylates RB1 at 'Lys-860', Shows even higher methyltransferase activity on p53/TP53, Specifically methylates histone H3 'Lys-4' (H3K4me) and dimethylates histone H3 'Lys-36' (H3K36me2), including p53/TP53 and RB1, leading to decreased DNA-binding activity and subsequent transcriptional regulation activity of p53/TP53, Protein-lysine N-methyltransferase that methylates both histones and non-histone proteins |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Synonyms: |
HSKM-B ZMYND14 KMT3C |
| Also known as: |
SMYD2 Polyclonal Antibody |
| Other name: |
Anti-SMYD2 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
SMYD2 |
| Short name: |
Anti-SMYD2 (Polyclonal) |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Alternative name: |
antibody to-SMYD2 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
20982 |
| Gene: |
SMYD2 |
More about : SMYD2 |
| Long gene name: |
SET and MYND domain containing 2 |
| Locus: |
1q32, 3 |
| Discovery year: |
2003-04-28 |
| GenBank acession: |
AF226053 |
| Entrez gene record: |
56950 |
| RefSeq identity: |
NM_020197 |
| Classification: |
Lysine methyltransferases Zinc fingers MYND-type |
| Havana BLAST/BLAT: |
OTTHUMG00000037066 |