| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
GAP43 Ser41 |
| Specificity: |
This antibody reacts specifically with GAP43 (Ser41) |
| Modification: |
Phosphorylation |
| Modification site: |
Ser41 |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic phosphopeptide derived from human GAP43 around the phosphorylation site of Ser41 |
| Gene ID: |
2596 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, Jul 2008], This protein is considered a crucial component of an effective regenerative response in the nervous system, [provided by RefSeq, The protein encoded by this gene has been termed a 'growth' or 'plasticity' protein because it is expressed at high levels in neuronal growth cones during development and axonal regeneration |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
B-50 PP46 |
| Also known as: |
GAP43 (Ser41) Polyclonal Antibody |
| Other name: |
Anti-GAP43 (Ser41) Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
GAP43 (Ser41) |
| Short name: |
Anti-GAP43 (Ser41) (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-growth associated protein 43 (Ser41) (polyclonal) |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
B-50 and PP46, Cell surfaces, GAP43 and IDBG-50973 and ENSG00000172020 and 2596, GAP43 and IDBG-632650 and ENSBTAG00000006451 and 281777, Gap43 and IDBG-160941 and ENSMUSG00000047261 and 14432, calmodulin binding, this GO :0005515 and protein binding and molecular function this GO :0005516 and calmodulin binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0007205 and protein kinase C-activating G-protein coupled receptor signaling pathway and biological process this GO :0007399 and nervous system development and biological process this GO :0007411 and axon guidance and biological process this GO :0009611 and response to wounding and biological process this GO :0010001 and glial cell differentiation and biological process this GO :0016198 and axon choice point recognition and biological process this GO :0030054 and cell junction and cellular component this GO :0030424 and axon and cellular component this GO :0031527 and filopodium membrane and cellular component this GO :0032584 and growth cone membrane and cellular component this GO :0040008 and regulation of growth and biological process this GO :0042246 and tissue regeneration and biological process this GO :0045165 and cell fate commitment and biological process this GO :0045202 and synapse and cellular component this GO :0051489 and regulation of filopodium assembly and biological process this GO :0071944 and cell periphery and cellular component, this GO :0005515 : protein binding, this GO :0005515 : protein binding and also this GO :0005516 : calmodulin binding, this GO :0005516 : calmodulin binding, growth associated protein 43 |
| Identity: |
4140 |
| Gene: |
GAP43 |
More about : GAP43 |
| Long gene name: |
growth associated protein 43 |
| Synonyms name: |
neuron growth-associated protein 43 neuromodulin nerve growth-related peptide GAP43 axonal membrane protein GAP-43 protein F1 calmodulin-binding protein P-57 neural phosphoprotein B-50 |
| Locus: |
3q13, 31 |
| Discovery year: |
1990-07-10 |
| Entrez gene record: |
2596 |
| Pubmed identfication: |
3272162 8231732 |
| RefSeq identity: |
NM_002045 |
| Havana BLAST/BLAT: |
OTTHUMG00000133758 |