| Long name: |
CRK (Ser41) Primary Polyclonal Antibody |
| Also known as: |
CRK (Ser41) PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
CRK Ser41 |
| Specificity: |
This is a highly specific antibody against CRK Ser41 |
| Modification(s): |
Phosphorylation |
| Modification site(s): |
Ser41 |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic phosphopeptide derived from human CRK around the phosphorylation site of Ser41 [DS(p-S)TS] |
| Gene ID number: |
1398 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation, The product of this gene has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, Two alternative transcripts encoding different isoforms with distinct biological activity have been described, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction, This gene encodes a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
Adapter molecule crk, Avian sarcoma virus CT10 v crk oncogene homolog, CRK CRK isoform 2, CRK isoform II, CRKII, CRK_HUMAN, Proto oncogene C crk, p-CRKS41, p38, v crk avian sarcoma virus CT10 oncogene homolog , v crk sarcoma virus CT10 oncogene homolog, v crk sarcoma virus CT10 oncogene homolog avian, p-CRKSer41 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
CRK (Ser41) |
| Short name: |
CRK (Ser41) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
CRK (Ser41) (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
2362 |
| Gene: |
CRK |
More about : CRK |
| Long gene name: |
CRK proto-oncogene, adaptor protein |
| Synonyms gene name: |
v-crk avian sarcoma virus CT10 oncogene homolog |
| Locus: |
17p13, 3 |
| Discovery year: |
1992-12-07 |
| GenBank acession: |
D10656 |
| Entrez gene record: |
1398 |
| Pubmed identfication: |
1690891 |
| RefSeq identity: |
NM_016823 |
| Classification: |
SH2 domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000090317 |