| PCR for diagnosis: |
MTHFR 1298A>, MTR 2756 A>, MTRR 66 A>, qPCR or real-time PCR of 48 Tests per screening, C (Glu429Ala), G (Asp3919Gly), G (Ile22Met) is used as PCR kit for molecular diagnostics with elecrtophoresis, T (Ala222Val), This Folates Methabolism Panel Real Time PCR kit for detection of 4 mutations: MTHFR 677 C> |
| ISO CE marked fro IVD: |
CE marked with the in vitro diagnostic medical divices requirements Annex 2 of list B of the laboratory Directive 98/79/EC and can be used for diagnosis of viruses, The PCR kit is ISO 9001:2008 and ISO 13485:2012, The kit inculde all reagents for PCR or RT-PCR of viral DNA or RNA, in vitro PCR Diagnostics, This molecular diagnostic PCR kit is CE approved and complies with the Directive 98/79/EC for IVD |
| Description: |
The assay must be performed following the protocol, The detections of the targets with this kit is a type of test that can be performed on any target containing biological samples after clean up of interfering agents |
| Group: |
polymerase chain reaction, PCR |
| About: |
The mores specific the lower the yield, TAQ or Pfu or Pfx or other enzymes are used for polycmerase chain reaction and have different specificity |
| Gene target: |
C (Glu429Ala) MTR 2756 A>, Folates Methabolism Panel Real Time kit for of 4 mutations: MTHFR 677 C>, G (Asp3919Gly) MTRR 66 A>, G (Ile22Met), T (Ala222Val) MTHFR 1298A> |
| Short name: |
C (Glu429Ala) MTR 2756 A>, Folates Methabolism Panel Real Time PCR kit for of 4 mutations: MTHFR 677 C>, G (Asp3919Gly) MTRR 66 A>, G (Ile22Met), T (Ala222Val) MTHFR 1298A> |
| Technique: |
For real time PCR the cycle threshold Ct values willneed to be set before the experiment, Than the RT-PCR starts from RNA and real time PCR quantitates the cDNA so the RNA in the sample on given time of the experiment, The , (PCR) amplifies the DNA in your sample, detection, polymerase chain reaction |
| Alternative name: |
MTHFR 1298A>, MTR 2756 A>, MTRR 66 A>, C (Glu429Ala), Folates Methabolism Panel Quantitative real-time PCR test reagent kit to measure quantification on 4 mutations: MTHFR 677 C>, G (Asp3919Gly), G (Ile22Met), T (Ala222Val) |
| Alternative technique: |
dna-amplification |
| Identity: |
7436 |
| Gene: |
MTHFR |
More about : MTHFR |
| Long gene name: |
methylenetetrahydrofolate reductase |
| Synonyms gene name: |
5, 10-methylenetetrahydrofolate reductase (NADPH) methylenetetrahydrofolate reductase (NAD(P)H) |
| Locus: |
1p36, 22 |
| Discovery year: |
1994-07-15 |
| GenBank acession: |
BC053509 |
| Entrez gene record: |
4524 |
| Pubmed identfication: |
7920641 |
| RefSeq identity: |
NM_005957 |
| Havana BLAST/BLAT: |
OTTHUMG00000002277 |
| Locus Specific Databases: |
LRG_726 |