| PCR for diagnosis: |
HFE 193 A>, HFE 845 G>, qPCR or real-time PCR of 50 Tests per screening, A (C282Y) is used as PCR kit for molecular diagnostics with elecrtophoresis, G (H63D), T (S65C), This Haemochromatosis Panel Real Time PCR kit for detection of 3 mutations: HFE 187 C> |
| ISO CE marked fro IVD: |
CE marked with the in vitro diagnostic medical divices requirements Annex 2 of list B of the laboratory Directive 98/79/EC and can be used for diagnosis of viruses, The PCR kit is ISO 9001:2008 and ISO 13485:2012, The kit inculde all reagents for PCR or RT-PCR of viral DNA or RNA, in vitro PCR Diagnostics, This molecular diagnostic PCR kit is CE approved and complies with the Directive 98/79/EC for IVD |
| Description: |
The assay must be performed following the protocol, The detections of the targets with this kit is a type of test that can be performed on any target containing biological samples after clean up of interfering agents |
| Group: |
polymerase chain reaction, PCR |
| About: |
The mores specific the lower the yield, TAQ or Pfu or Pfx or other enzymes are used for polycmerase chain reaction and have different specificity |
| Gene target: |
A (C282Y), G (H63D) HFE 193 A>, Haemochromatosis Panel Real Time kit for of 3 mutations: HFE 187 C>, T (S65C) HFE 845 G> |
| Short name: |
A (C282Y), G (H63D) HFE 193 A>, Haemochromatosis Panel Real Time PCR kit for of 3 mutations: HFE 187 C>, T (S65C) HFE 845 G> |
| Technique: |
For real time PCR the cycle threshold Ct values willneed to be set before the experiment, Than the RT-PCR starts from RNA and real time PCR quantitates the cDNA so the RNA in the sample on given time of the experiment, The , (PCR) amplifies the DNA in your sample, detection, polymerase chain reaction |
| Alternative name: |
hemochromatosis 193 A>, hemochromatosis 845 G>, A (C282Y), G (H63D), Haemochromatosis Panel Quantitative real-time PCR test reagent kit to measure quantification on 3 mutations: hemochromatosis 187 C>, T (S65C) |
| Alternative technique: |
dna-amplification |
| Alternative to gene target: |
BT, HFE and IDBG-67372 and ENSG00000010704 and 3077, HFE1 and HH and HLA-H and MVCD7 and TFQTL2, Hfe and IDBG-136751 and ENSMUSG00000006611 and 15216, Plasma membranes, peptide antigen binding, this GO :0001916 and positive regulation of T cell mediated cytotoxicity and biological process this GO :0002474 and antigen processing and presentation of peptide antigen via MHC class I and biological process this GO :0005102 and receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005769 and early endosome and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006461 and protein complex assembly and biological process this GO :0006879 and cellular iron ion homeostasis and biological process this GO :0006955 and immune response and biological process this GO :0007565 and female pregnancy and biological process this GO :0010106 and cellular response to iron ion starvation and biological process this GO :0016021 and integral component of membrane and cellular component this GO :0019882 and antigen processing and presentation and biological process this GO :0031410 and cytoplasmic vesicle and cellular component this GO :0042446 and hormone biosynthetic process and biological process this GO :0042605 and peptide antigen binding and molecular function this GO :0042612 and MHC class I protein complex and cellular component this GO :0045177 and apical part of cell and cellular component this GO :0045178 and basal part of cell and cellular component this GO :0048471 and perinuclear region of cytoplasm and cellular component this GO :0055037 and recycling endosome and cellular component this GO :0055072 and iron ion homeostasis and biological process this GO :0060586 and multicellular organismal iron ion homeostasis and biological process this GO :0097459 and iron ion import into cell and biological process, this GO :0005102 : receptor binding, this GO :0005102 : receptor binding and also this GO :0005515 : protein binding and also this GO :0042605 : peptide antigen binding, this GO :0005515 : protein binding, this GO :0042605 : peptide antigen binding, 37142 and IDBG-635416 and ENSBTAG00000013065 and 497622, hemochromatosis |
| Identity: |
4886 |
| Gene: |
HFE |
More about : HFE |
| Long gene name: |
hemochromatosis |
| Synonyms: |
HLA-H |
| Synonyms name: |
high Fe |
| Locus: |
6p22, 2 |
| Discovery year: |
1986-01-01 |
| Entrez gene record: |
3077 |
| Pubmed identfication: |
3460331 |
| Classification: |
C1-set domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000016348 |
| Locus Specific Databases: |
ALSOD, the Amyotrophic Lateral Sclerosis Online Genetic Database LRG_748 |