| Category: |
Antibody |
| Concentration: |
pH7, with 0, 02% sodium azide, 3, 5 mg/ml in 1X TBS, 5% BSA (US sourced) and 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
NPC1 |
| Host animal: |
Goat (Capra aegagrus hircus) |
| Clonality: |
Polyclonal (goat origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA (peptide), WB |
| Recommended dilutions: |
5-1, 5ug/ml, ELISA (peptide) LOD: 1:128000, Western blot: 0 |
| Notes: |
Optimal dilution of the NPC1 antibody should be determined by the researcher |
| Intented use: |
This NPC1 antibodyis to be used only for research purposes and not for diagnostics |
| Gene ID #: |
4864 |
| Purity: |
Antigen affinity |
| Description: |
Additional name(s) for this target protein: Niemann Pick type C1 |
| Immunogen: |
Amino acids TYHTVLQTSADFID were used as the immunogen for this NPC1 antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot and store the NPC1 antibody at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
NPC1 |
| Short name: |
NPC1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
classification C1 (Antibody to), Niemann-Pick disease |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
NPC, NPC1 and IDBG-1600 and ENSG00000141458 and 4864, NPC1 and IDBG-643938 and ENSBTAG00000015195 and 286772, Npc1 and IDBG-128877 and ENSMUSG00000024413 and 18145, cholesterol binding, nuclei, this GO :0004872 and receptor activity and molecular function this GO :0004888 and transmembrane signaling receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005635 and nuclear envelope and cellular component this GO :0005764 and lysosome and cellular component this GO :0005765 and lysosomal membrane and cellular component this GO :0005768 and endosome and cellular component this GO :0005783 and endoplasmic reticulum and cellular component this GO :0005794 and this GO lgi apparatus and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006486 and protein glycosylation and biological process this GO :0006897 and endocytosis and biological process this GO :0006914 and autophagy and biological process this GO :0007041 and lysosomal transport and biological process this GO :0007165 and signal transduction and biological process this GO :0007628 and adult walking behavior and biological process this GO :0008158 and hedgehog receptor activity and molecular function this GO :0008203 and cholesterol metabolic process and biological process this GO :0008206 and bile acid metabolic process and biological process this GO :0015248 and sterol transporter activity and molecular function this GO :0015485 and cholesterol binding and molecular function this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0016242 and negative regulation of macroautophagy and biological process this GO :0030301 and cholesterol transport and biological process this GO :0031579 and membrane raft organization and biological process this GO :0031902 and late endosome membrane and cellular component this GO :0031982 and vesicle and cellular component this GO :0033344 and cholesterol efflux and biological process this GO :0042493 and response to drug and biological process this GO :0042632 and cholesterol homeostasis and biological process this GO :0045121 and membrane raft and cellular component this GO :0046686 and response to cadmium ion and biological process this GO :0048471 and perinuclear region of cytoplasm and cellular component this GO :0060548 and negative regulation of cell death and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0071383 and cellular response to steroid hormone stimulus and biological process this GO :0071404 and cellular response to low-density lipoprotein particle stimulus and biological process this GO :0090150 and establishment of protein localization to membrane and biological process, this GO :0004872 : receptor activity, this GO :0004872 : receptor activity and also this GO :0004888 : transmembrane signaling receptor activity and also this GO :0005515 : protein binding and also this GO :0008158 : hedgehog receptor activity and also this GO :0015248 : sterol transporter activity and also this GO :0015485 : cholesterol binding, this GO :0004888 : transmembrane signaling receptor activity, this GO :0005515 : protein binding, this GO :0008158 : hedgehog receptor activity, this GO :0015248 : sterol transporter activity, this GO :0015485 : cholesterol binding, type C1, Niemann-Pick disease |
| Identity: |
7897 |
| Gene: |
NPC1 |
More about : NPC1 |
| Long gene name: |
NPC intracellular cholesterol transporter 1 |
| Synonyms gene name: |
Niemann-Pick disease, type C1 |
| Locus: |
18q11, 2 |
| Discovery year: |
1993-04-13 |
| GenBank acession: |
AF002020 |
| Entrez gene record: |
4864 |
| Pubmed identfication: |
8446622 |
| RefSeq identity: |
NM_000271 |
| Havana BLAST/BLAT: |
OTTHUMG00000131873 |