| known also as: |
NPC), Niemann-Pick C1, Niemann-Pick C1 Protein Precursor, Type C1 (NPC1, Anti-Niemann-Pick Disease |
| known also as: |
NPC), Niemann-Pick C1, Niemann-Pick C1 Protein Precursor, Type C1 (NPC1, Niemann-Pick Disease |
| known also as: |
NPC), Niemann-Pick C1, Niemann-Pick C1 Protein Precursor, Type C1 (NPC1, Niemann-Pick Disease |
| known also as: |
Type C1, Niemann-Pick Disease |
| known also as: |
NPC), Niemann-Pick C1, Niemann-Pick C1 Protein Precursor, Type C1 (NPC1, Anti -Niemann-Pick Disease |
| Other names: |
N/A, Niemann-Pick C1 protein, Niemann-Pick C1 protein, Niemann-Pick disease, OTTHUMP00000162699, type C1, type C1, Niemann-Pick disease |
| Other gene names: |
FLJ98532, N/A, NPC, NPC1, NPC1 |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Host organism: |
Source: Human, Host: Rabbit |
| Species reactivity: |
Human, Mouse, Hamster |
| Specificity and cross-reactivity: |
Species Crossreactivity: This antibody reacts with human, and hamster protein, mouse, This antibody is specific for NPC1 protein |
| Purification method: |
Affinity Purified by immunoaffinity chromatography |
| Form/Appearance: |
pH 7, 2, Supplied as a liquid in PBS |
| Storage and shipping: |
Aliquots are stable for at least 12 months productone should be stored at -20 degrees Celsius, For long-term storage and to avoid repeated freezing and thawing, For maximum recovery of product, Further dilutions can be made in assay buffer, aliquot and For optimal long term storage, centrifuge the original vial after thawing and prior to removing the cap, productone should be kept at -20 degrees Celsius, Store at 4 degrees Celsius for short term storage |
| Tested for:: |
Immunofluorescence (IF), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB) |
| Description: |
also called a , is a type of partially differentiated, usually , Precursor cell, blast, blast cell , cell that has lost most or all of the , multipotency, or simply , stem cell , unipotent |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS Polyclonals_1 they should be stored frozen at - 24° |
| Gene target: |
C1 (NPC1, NPC), Niemann-Pick C1, Niemann-Pick C1 Protein Precursor, Niemann-Pick Disease |
| Short name: |
C1 (NPC1, Niemann-Pick C1, Niemann-Pick C1 Protein NPC) Antibody, Niemann-Pick Disease |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
NPC) (Antibody to), Niemann-Pick C1, Niemann-Pick C1 Protein Precursor, classification C1, classification C1 (Niemann-Pick disease, Niemann-Pick Disease |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
NPC, NPC1 and IDBG-1600 and ENSG00000141458 and 4864, NPC1 and IDBG-643938 and ENSBTAG00000015195 and 286772, Npc1 and IDBG-128877 and ENSMUSG00000024413 and 18145, cholesterol binding, nuclei, this GO :0004872 and receptor activity and molecular function this GO :0004888 and transmembrane signaling receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005635 and nuclear envelope and cellular component this GO :0005764 and lysosome and cellular component this GO :0005765 and lysosomal membrane and cellular component this GO :0005768 and endosome and cellular component this GO :0005783 and endoplasmic reticulum and cellular component this GO :0005794 and this GO lgi apparatus and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006486 and protein glycosylation and biological process this GO :0006897 and endocytosis and biological process this GO :0006914 and autophagy and biological process this GO :0007041 and lysosomal transport and biological process this GO :0007165 and signal transduction and biological process this GO :0007628 and adult walking behavior and biological process this GO :0008158 and hedgehog receptor activity and molecular function this GO :0008203 and cholesterol metabolic process and biological process this GO :0008206 and bile acid metabolic process and biological process this GO :0015248 and sterol transporter activity and molecular function this GO :0015485 and cholesterol binding and molecular function this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0016242 and negative regulation of macroautophagy and biological process this GO :0030301 and cholesterol transport and biological process this GO :0031579 and membrane raft organization and biological process this GO :0031902 and late endosome membrane and cellular component this GO :0031982 and vesicle and cellular component this GO :0033344 and cholesterol efflux and biological process this GO :0042493 and response to drug and biological process this GO :0042632 and cholesterol homeostasis and biological process this GO :0045121 and membrane raft and cellular component this GO :0046686 and response to cadmium ion and biological process this GO :0048471 and perinuclear region of cytoplasm and cellular component this GO :0060548 and negative regulation of cell death and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0071383 and cellular response to steroid hormone stimulus and biological process this GO :0071404 and cellular response to low-density lipoprotein particle stimulus and biological process this GO :0090150 and establishment of protein localization to membrane and biological process, this GO :0004872 : receptor activity, this GO :0004872 : receptor activity and also this GO :0004888 : transmembrane signaling receptor activity and also this GO :0005515 : protein binding and also this GO :0008158 : hedgehog receptor activity and also this GO :0015248 : sterol transporter activity and also this GO :0015485 : cholesterol binding, this GO :0004888 : transmembrane signaling receptor activity, this GO :0005515 : protein binding, this GO :0008158 : hedgehog receptor activity, this GO :0015248 : sterol transporter activity, this GO :0015485 : cholesterol binding, type C1, Niemann-Pick disease |
| Identity: |
7897 |
| Gene: |
NPC1 |
More about : NPC1 |
| Long gene name: |
NPC intracellular cholesterol transporter 1 |
| Synonyms gene name: |
Niemann-Pick disease, type C1 |
| Locus: |
18q11, 2 |
| Discovery year: |
1993-04-13 |
| GenBank acession: |
AF002020 |
| Entrez gene record: |
4864 |
| Pubmed identfication: |
8446622 |
| RefSeq identity: |
NM_000271 |
| Havana BLAST/BLAT: |
OTTHUMG00000131873 |