| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
EPOR |
| Specificity: |
This antibody reacts specifically with EPOR |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Cytoplasm |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human EPOR |
| Gene ID: |
2057 |
| Swiss Prot: |
P19235 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
EPOR dimerizes triggering the JAK2/STAT5 signaling cascade, In some cell types, Isoform EPOR-T acts as a dominant-negative receptor of EPOR-mediated signaling, May also activate the LYN tyrosine kinase, Mediates erythropoietin-induced erythroblast proliferation and differentiation, Upon EPO stimulation, can also activate STAT1 and STAT3, Receptor for erythropoietin |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Also known as: |
EPOR Polyclonal Antibody |
| Other name: |
Anti-EPOR Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
EPOR |
| Short name: |
Anti-EPOR (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-erythropoietin receptor (polyclonal) |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
EPO-R, EPOR and IDBG-29281 and ENSG00000187266 and 2057, EPOR and IDBG-643528 and ENSBTAG00000008197 and 281144, Epor and IDBG-142378 and ENSMUSG00000006235 and 13857, Extracellular, identical protein binding, this GO :0004888 and transmembrane signaling receptor activity and molecular function this GO :0004900 and erythropoietin receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0007165 and signal transduction and biological process this GO :0007420 and brain development and biological process this GO :0007507 and heart development and biological process this GO :0016021 and integral component of membrane and cellular component this GO :0038162 and erythropoietin-mediated signaling pathway and biological process this GO :0042802 and identical protein binding and molecular function this GO :0045087 and innate immune response and biological process this GO :0046697 and decidualization and biological process, this GO :0004888 : transmembrane signaling receptor activity, this GO :0004888 : transmembrane signaling receptor activity and also this GO :0004900 : erythropoietin receptor activity and also this GO :0005515 : protein binding and also this GO :0042802 : identical protein binding, this GO :0004900 : erythropoietin receptor activity, this GO :0005515 : protein binding, this GO :0042802 : identical protein binding, erythropoietin receptor |
| Identity: |
3416 |
| Gene: |
EPOR |
More about : EPOR |
| Long gene name: |
erythropoietin receptor |
| Locus: |
19p13, 2 |
| Discovery year: |
1990-05-14 |
| GenBank acession: |
M34986 |
| Entrez gene record: |
2057 |
| Classification: |
Fibronectin type III domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000182027 |