| Long name: |
ALEXA FLUOR 488 Conjugated, EPOR Polyclonal Antibody |
| Also known as: |
Anti-EPOR PAb ALEXA FLUOR 488 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
488, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
EPOR |
| Specificity: |
This is a highly specific antibody against EPOR |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
330-380/508 |
| Subcellular location: |
Cytoplasm |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human EPOR |
| Gene ID Number: |
2057 |
| Swiss Prot: |
P19235 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
EPOR dimerizes triggering the JAK2/STAT5 signaling cascade, In some cell types, Isoform EPOR-T acts as a dominant-negative receptor of EPOR-mediated signaling, May also activate the LYN tyrosine kinase, Mediates erythropoietin-induced erythroblast proliferation and differentiation, Upon EPO stimulation, can also activate STAT1 and STAT3, Receptor for erythropoietin |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
499nm/519nm |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the EPOR Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
EPOR |
| Short name: |
EPOR Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 488 |
| Alternative name: |
ALEXA FLUOR 488, erythropoietin receptor (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
EPO-R, EPOR and IDBG-29281 and ENSG00000187266 and 2057, EPOR and IDBG-643528 and ENSBTAG00000008197 and 281144, Epor and IDBG-142378 and ENSMUSG00000006235 and 13857, Extracellular, identical protein binding, this GO :0004888 and transmembrane signaling receptor activity and molecular function this GO :0004900 and erythropoietin receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0007165 and signal transduction and biological process this GO :0007420 and brain development and biological process this GO :0007507 and heart development and biological process this GO :0016021 and integral component of membrane and cellular component this GO :0038162 and erythropoietin-mediated signaling pathway and biological process this GO :0042802 and identical protein binding and molecular function this GO :0045087 and innate immune response and biological process this GO :0046697 and decidualization and biological process, this GO :0004888 : transmembrane signaling receptor activity, this GO :0004888 : transmembrane signaling receptor activity and also this GO :0004900 : erythropoietin receptor activity and also this GO :0005515 : protein binding and also this GO :0042802 : identical protein binding, this GO :0004900 : erythropoietin receptor activity, this GO :0005515 : protein binding, this GO :0042802 : identical protein binding, erythropoietin receptor |
| Identity: |
3416 |
| Gene: |
EPOR |
More about : EPOR |
| Long gene name: |
erythropoietin receptor |
| Locus: |
19p13, 2 |
| Discovery year: |
1990-05-14 |
| GenBank acession: |
M34986 |
| Entrez gene record: |
2057 |
| Classification: |
Fibronectin type III domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000182027 |