| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
CD13/APN/ANPEN |
| Specificity: |
This antibody reacts specifically with CD13/APN/ANPEN |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Cell membrane, Cytoplasm |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human CD13 |
| Gene ID: |
290 |
| Swiss Prot: |
P15144 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Found to cleave antigen peptides bound to major histocompatibility complex class II molecules of presenting cells and to degrade neurotransmitters at synaptic junctions, In case of human coronavirus 229E (HCoV-229E) infection, Is also implicated as a regulator of IL-8 bioavailability in the endometrium, Is used as a marker for acute myeloid leukemia and plays a role in tumor invasion, May be involved in the metabolism of regulatory peptides of diverse cell types, May play a critical role in the pathogenesis of cholesterol gallstone disease, Mediates as well human cytomegalovirus (HCMV) infection, Plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases, and chemokines, and therefore may contribute to the regulation of angiogenesis, neuropeptides, responsible for the processing of peptide hormones, serves as receptor for HCoV-229E spike glycoprotein, such as angiotensin III and IV, Broad specificity aminopeptidase |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
LAP1 gp150 p150 |
| Also known as: |
CD13/APN/ANPEN Polyclonal Antibody |
| Other name: |
Anti-CD13/APN/ANPEN Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
CD13/APN/ANPEN |
| Short name: |
Anti-CD13/APN/ANPEN (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-CD13/APN/ANPEN (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
500 |
| Gene: |
ANPEP |
More about : ANPEP |
| Long gene name: |
alanyl aminopeptidase, membrane |
| Synonyms gene: |
CD13 PEPN |
| Synonyms gene name: |
alanyl (membrane) aminopeptidase |
| Synonyms name: |
aminopeptidase N aminopeptidase M microsomal aminopeptidase membrane alanyl aminopeptidase |
| Locus: |
15q26, 1 |
| Discovery year: |
1989-02-28 |
| GenBank acession: |
M22324 |
| Entrez gene record: |
290 |
| Pubmed identfication: |
2428842 1977688 |
| Classification: |
CD molecules Aminopeptidases |
| Havana BLAST/BLAT: |
OTTHUMG00000149814 |