| Long name: |
CD13/APN/ANPEN Primary Polyclonal Antibody |
| Also known as: |
CD13/APN/ANPEN PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
CD13/APN/ANPEN |
| Specificity: |
This is a highly specific antibody against CD13/APN/ANPEN |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
910-960/967 |
| Subcellular location: |
Cell membrane, Cytoplasm |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CD13 |
| Gene ID number: |
290 |
| Swiss Prot: |
P15144 |
| Tested Applications: |
FCM, IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
FCM(1:20-100), IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Found to cleave antigen peptides bound to major histocompatibility complex class II molecules of presenting cells and to degrade neurotransmitters at synaptic junctions, In case of human coronavirus 229E (HCoV-229E) infection, Is also implicated as a regulator of IL-8 bioavailability in the endometrium, Is used as a marker for acute myeloid leukemia and plays a role in tumor invasion, May be involved in the metabolism of regulatory peptides of diverse cell types, May play a critical role in the pathogenesis of cholesterol gallstone disease, Mediates as well human cytomegalovirus (HCMV) infection, Plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases, and chemokines, and therefore may contribute to the regulation of angiogenesis, neuropeptides, responsible for the processing of peptide hormones, serves as receptor for HCoV-229E spike glycoprotein, such as angiotensin III and IV, Broad specificity aminopeptidase |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
ANPEP, AP-M, AP-N, Alanyl aminopeptidase, Aminopeptidase M, Aminopeptidase N, CD13, GP150, LAP1, Microsomal aminopeptidase, Myeloid plasma membrane glycoprotein CD13, P150, PEPN, hAPN, APN |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
CD13/APN/ANPEN |
| Short name: |
CD13/APN/ANPEN Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
CD13/APN/ANPEN (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
500 |
| Gene: |
ANPEP |
More about : ANPEP |
| Long gene name: |
alanyl aminopeptidase, membrane |
| Synonyms gene: |
CD13 PEPN |
| Synonyms gene name: |
alanyl (membrane) aminopeptidase |
| Synonyms: |
LAP1 gp150 p150 |
| Synonyms name: |
aminopeptidase N aminopeptidase M microsomal aminopeptidase membrane alanyl aminopeptidase |
| Locus: |
15q26, 1 |
| Discovery year: |
1989-02-28 |
| GenBank acession: |
M22324 |
| Entrez gene record: |
290 |
| Pubmed identfication: |
2428842 1977688 |
| Classification: |
CD molecules Aminopeptidases |
| Havana BLAST/BLAT: |
OTTHUMG00000149814 |