| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
DAP-5/p97 |
| Specificity: |
This antibody reacts specifically with DAP-5/p97 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human DAP-5 |
| Gene ID: |
1982 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Compared with eIF4G, DAP5 is cleaved at Asp790, DAP5 lacks the N-terminal region necessary for cap-dependent translation and has a unique C-terminal part functioning as a regulator for interferon-gamma induced cell death, During apoptosis, The C-terminal truncated form of DAP5 functions as a cap-independent translation initiation factor responsible for the mediation of its own translation during apoptosis, Death Associated Protein 5 (DAP5) is a 97 kDa protein with high amino acid sequence homology to Eukaryotic Translation Initiation Factor 4G (eIF4G) |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
Death associated protein 5, Eukaryotic translation initiation factor 4 gamma 2, Nat1, Novel APOBEC-1 target 1, Translation repressor NAT1, Death Associated Protein-5 |
| Also known as: |
DAP-5/p97 Polyclonal Antibody |
| Other name: |
Anti-DAP-5/p97 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
DAP-5/p97 |
| Short name: |
Anti-DAP-5/p97 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-death-associated protein-5/p97 (polyclonal) |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
DAP and IDBG-12509 and ENSG00000112977 and 1611, DAP and IDBG-631574 and ENSBTAG00000006346 and 616066, DNA-templated and biological process this GO :0070513 and death domain binding and molecular function this GO :0097190 and apoptotic signaling pathway and biological process, Dap and IDBG-132573 and ENSMUSG00000039168 and 223453, death domain binding, multiple, this GO :0006914 and autophagy and biological process this GO :0006915 and apoptotic process and biological process this GO :0006919 and activation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0010507 and negative regulation of autophagy and biological process this GO :0032088 and negative regulation of NF-kappaB transcription factor activity and biological process this GO :0034198 and cellular response to amino acid starvation and biological process this GO :0045892 and negative regulation of transcription, this GO :0070513 : death domain binding, this GO :0070513 : death domain binding, death-associated protein |