| Long name: |
FITC Conjugated, DAP-5/p97 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
DAP-5/p97 |
| Specificity: |
This is a highly specific antibody against DAP-5/p97 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human DAP-5 |
| Gene ID number: |
1982 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Compared with eIF4G, DAP5 is cleaved at Asp790, DAP5 lacks the N-terminal region necessary for cap-dependent translation and has a unique C-terminal part functioning as a regulator for interferon-gamma induced cell death, During apoptosis, The C-terminal truncated form of DAP5 functions as a cap-independent translation initiation factor responsible for the mediation of its own translation during apoptosis, Death Associated Protein 5 (DAP5) is a 97 kDa protein with high amino acid sequence homology to Eukaryotic Translation Initiation Factor 4G (eIF4G) |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
Death associated protein 5, Eukaryotic translation initiation factor 4 gamma 2, Nat1, Novel APOBEC-1 target 1, Translation repressor NAT1, Death Associated Protein-5 |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
DAP-5/p97 Conjugated |
| Short name: |
FITC Conjugated, DAP-5/p97 Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, death-associated protein-5/p97 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
DAP and IDBG-12509 and ENSG00000112977 and 1611, DAP and IDBG-631574 and ENSBTAG00000006346 and 616066, DNA-templated and biological process this GO :0070513 and death domain binding and molecular function this GO :0097190 and apoptotic signaling pathway and biological process, Dap and IDBG-132573 and ENSMUSG00000039168 and 223453, death domain binding, multiple, this GO :0006914 and autophagy and biological process this GO :0006915 and apoptotic process and biological process this GO :0006919 and activation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0010507 and negative regulation of autophagy and biological process this GO :0032088 and negative regulation of NF-kappaB transcription factor activity and biological process this GO :0034198 and cellular response to amino acid starvation and biological process this GO :0045892 and negative regulation of transcription, this GO :0070513 : death domain binding, this GO :0070513 : death domain binding, death-associated protein |