| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
DAP Kinase 2 Ser318 |
| Specificity: |
This antibody reacts specifically with DAP Kinase 2 (Ser318) |
| Modification: |
Phosphorylation |
| Modification site: |
Ser318 |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic phosphopeptide derived from human DAP Kinase 2 around the phosphorylation site of Ser318 |
| Gene ID: |
23604 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Overexpression of DAPK2 significantly induced the morphological changes characteristic of apoptosis, Results indicate that DAPK2 is an additional member of DAP kinase family involved in apoptotic signaling, a protein kinase involved in apoptosis, Protein kinase termed (DAPK2) dependant on calcium/calmodulin (Ca2+/CaM) contains an N-terminal protein kinase domain followed by a conserved CaM-binding domain with significant homologies to those of DAP kinase |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Also known as: |
DAP Kinase 2 (Ser318) Antibody |
| Other name: |
Anti-DAP Kinase 2 (Ser318) |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
DAP Kinase 2 (Ser318) |
| Short name: |
Anti-DAP Kinase 2 (Ser318) Fluor 594 |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-death-associated protein phosphorylation catalyst 2 (Ser318) |
| Alternative to gene target: |
DAP and IDBG-12509 and ENSG00000112977 and 1611, DAP and IDBG-631574 and ENSBTAG00000006346 and 616066, DNA-templated and biological process this GO :0070513 and death domain binding and molecular function this GO :0097190 and apoptotic signaling pathway and biological process, Dap and IDBG-132573 and ENSMUSG00000039168 and 223453, death domain binding, multiple, this GO :0006914 and autophagy and biological process this GO :0006915 and apoptotic process and biological process this GO :0006919 and activation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0010507 and negative regulation of autophagy and biological process this GO :0032088 and negative regulation of NF-kappaB transcription factor activity and biological process this GO :0034198 and cellular response to amino acid starvation and biological process this GO :0045892 and negative regulation of transcription, this GO :0070513 : death domain binding, this GO :0070513 : death domain binding, death-associated protein |
| Identity: |
2672 |
| Gene: |
DAP |
More about : DAP |
| Long gene name: |
death associated protein |
| Locus: |
5p15, 2 |
| Discovery year: |
1995-04-27 |
| GenBank acession: |
X76105 |
| Entrez gene record: |
1611 |
| Pubmed identfication: |
8530096 7828849 |
| RefSeq identity: |
NM_004394 |
| Havana BLAST/BLAT: |
OTTHUMG00000131041 |