| Catalog number: | GENTAUR-58be5db0a9849 |
|---|---|
| Price: | 332 € |
| Supplier: | Bioss Primary Conjugated Antibodies. |
| Product name: | Anti-GPCR G2A (Polyclonal), ALEXA Fluor 594 |
| Quantity: | 100ul |
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| Type: | Conjugated Primary Antibody |
|---|---|
| Conjugated with: | 594, ALEXA FLUOR® |
| Host organism: | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: | GPCR G2A |
| Specificity: | This antibody reacts specifically with GPCR G2A |
| Modification: | No modification has been applied to this antibody |
| Modification site: | None |
| Clonality: | Polyclonal Antibody |
| Clone: | Polyclonal Antibodies |
| Concentration: | 1ug per 1ul |
| Subcellular locations: | Extracellular |
| Antigen Source: | KLH conjugated synthetic peptide derived from human G Protein Coupled Receptor G2A |
| Gene ID: | 29933 |
| Applications: | IF(IHC-P) |
| Applications with corresponding dilutions: | IF(IHC-P)(1:50-200) |
| Cross reactive species: | Human (Homo sapiens) |
| Cross Reactive Species details: | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: | Ectopic expression of a G2A fusion protein in NIH/3T3 fibroblasts induces a cell cycle arrest that is consistent with a block at the G2/M transition (1, G2A is also able to attenuate the proliferative effects of Bcr-Abl, G2A is expressed throughout T cell maturation, G2A is predominantly expressed in hematopoietic tissues and in hematopoietic stem cells, The amino acid sequence of G2A contains a destruction box motif that is consistently observed in cyclins, a chimeric tyrosine kinase oncogene, and it is further increased in response to T-cell activation (3), and it is more highly detected in pro-B cells, suggesting that G2A possesses anti-oncogenic properties (5), where it is required for ubiquitination and proteolytic degradation (6), while lower expression is observed in immature B cells and pre-B cells (1, 2), 4), G2A (for G2 accumulation) is a seven transmembrane G protein-coupled receptor that is upregulated in response to DNA damage and stress (1) |
| Purification method: | Purified by Protein A |
| Storage: | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: | 590nm/617nm |
| Synonyms: | GPCR TG1019 GPR170 |
| Also known as: | GPCR G2A Polyclonal Antibody |
| Other name: | Anti-GPCR G2A Polyclonal |
| Advisory: | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: | For facs or microscopy Alexa 1 conjugate |
| Conjugation: | Alexa Fluor |
| Group: | Polyclonals and antibodies |
| About: | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: | GPCR G2A |
| Short name: | Anti-GPCR G2A (Polyclonal) Fluor 594 |
| Technique: | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label: | ALEXA |
| Alternative name: | ALEXA Fluor 594, antibody to-GPCR G2A (polyclonal) |
| Alternative technique: | polyclonals |
| Identity: | 24884 |
| Gene: | OXER1 | More about : OXER1 |
| Long gene name: | oxoeicosanoid receptor 1 |
| Synonyms name: | 5-oxo-ETE acid G-protein-coupled receptor 1 OXE receptor |
| Locus: | 2p21 |
| Discovery year: | 2004-04-02 |
| GenBank acession: | AB083055 |
| Entrez gene record: | 165140 |
| Pubmed identfication: | 12065583 15001665 |
| RefSeq identity: | NM_148962 |
| Classification: | Leukotriene receptors |
| Havana BLAST/BLAT: | OTTHUMG00000128643 |
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