| Long name: |
FITC Conjugated, GPCR G2A Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
GPCR G2A |
| Specificity: |
This is a highly specific antibody against GPCR G2A |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Subcellular location: |
Extracellular |
| Source: |
KLH conjugated synthetic peptide derived from human G Protein Coupled Receptor G2A |
| Gene ID number: |
29933 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Ectopic expression of a G2A fusion protein in NIH/3T3 fibroblasts induces a cell cycle arrest that is consistent with a block at the G2/M transition (1, G2A is also able to attenuate the proliferative effects of Bcr-Abl, G2A is expressed throughout T cell maturation, G2A is predominantly expressed in hematopoietic tissues and in hematopoietic stem cells, The amino acid sequence of G2A contains a destruction box motif that is consistently observed in cyclins, a chimeric tyrosine kinase oncogene, and it is further increased in response to T-cell activation (3), and it is more highly detected in pro-B cells, suggesting that G2A possesses anti-oncogenic properties (5), where it is required for ubiquitination and proteolytic degradation (6), while lower expression is observed in immature B cells and pre-B cells (1, 2), 4), G2A (for G2 accumulation) is a seven transmembrane G protein-coupled receptor that is upregulated in response to DNA damage and stress (1) |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
GPCR TG1019 GPR170 |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
GPCR G2A Conjugated |
| Short name: |
FITC Conjugated, GPCR G2A Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, GPCR G2A (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
24884 |
| Gene: |
OXER1 |
More about : OXER1 |
| Long gene name: |
oxoeicosanoid receptor 1 |
| Synonyms name: |
5-oxo-ETE acid G-protein-coupled receptor 1 OXE receptor |
| Locus: |
2p21 |
| Discovery year: |
2004-04-02 |
| GenBank acession: |
AB083055 |
| Entrez gene record: |
165140 |
| Pubmed identfication: |
12065583 15001665 |
| RefSeq identity: |
NM_148962 |
| Classification: |
Leukotriene receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000128643 |