| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
GMP Synthase |
| Specificity: |
This antibody reacts specifically with GMP Synthase |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human GMP Synthase |
| Gene ID: |
8833 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
IMP is the branch point metabolite at which point the pathway diverges to the synthesis of either guanine or adenine nucleotides, In the guanine nucleotide pathway, Jul 2008], [provided by RefSeq, and GMP synthetase, namely IMP dehydrogenase (IMPD1), there are 2 enzymes involved in converting IMP to GMP, which catalyzes the amination of XMP to GMP, which catalyzes the oxidation of IMP to XMP, In the de novo synthesis of purine nucleotides |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
PNT5 GMP cN-II SPG65 |
| Also known as: |
GMP Synthase Polyclonal Antibody |
| Other name: |
Anti-GMP Synthase Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
GMP Synthase |
| Short name: |
Anti-GMP Synthase (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-GMP Synthase (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
8022 |
| Gene: |
NT5C2 |
More about : NT5C2 |
| Long gene name: |
5', cytosolic II , -nucleotidase |
| Synonyms gene: |
NT5B |
| Synonyms gene name: |
5', cytosolic type B , -nucleotidase (purine) |
| Synonyms name: |
nucleotidase , purine 5' |
| Locus: |
10q24, 32-q24, 33 |
| Discovery year: |
2000-06-16 |
| GenBank acession: |
D38524 |
| Entrez gene record: |
22978 |
| Pubmed identfication: |
7999131 24482476 |
| RefSeq identity: |
NM_012229 |
| Classification: |
5', -nucleotidases |
| Havana BLAST/BLAT: |
OTTHUMG00000018981 |