| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
Thromboxane synthase |
| Specificity: |
This antibody reacts specifically with Thromboxane synthase |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Cytoplasm |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human Thromboxane synthase |
| Gene ID: |
6916 |
| Swiss Prot: |
P24557 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Endothelial cells of placenta and epithelial cells in tonsils and bronchi also express this enzyme, In combination with the markers 27E10, RM 3/1 and 25F9, and for affinity purification of the enzyme, anti Thromboxane Synthase enables a more precise characterization of inflammatory processes in injured tissues, human tissue sections, isolated cells, or in vitro cell-cell interaction studies, Distribution of thromboxane synthase in human tissues: Thromboxane synthase is predominantly produced by macrophages or antigen presenting cells of the myelo-monocytic lineage as shown below, Thromboxane Synthase is a useful marker for the detection of native thromboxane synthase in smears |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
CYP5 CYP5A1 THAS TXS TXAS TS |
| Also known as: |
Thromboxane synthase Polyclonal Antibody |
| Other name: |
Anti-Thromboxane synthase Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
Thromboxane synthase |
| Short name: |
Anti-Thromboxane synthase (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-Thromboxane synthase (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
11609 |
| Gene: |
TBXAS1 |
More about : TBXAS1 |
| Long gene name: |
thromboxane A synthase 1 |
| Synonyms gene name: |
cytochrome P450, subfamily V) thromboxane A synthase 1 (platelet) , thromboxane A synthase 1 (platelet |
| Synonyms name: |
cytochrome P450, family 5, polypeptide 1 , subfamily A |
| Locus: |
7q34 |
| Discovery year: |
1992-10-07 |
| GenBank acession: |
L36085 |
| Entrez gene record: |
6916 |
| Pubmed identfication: |
1714723 8964509 |
| Classification: |
Cytochrome P450 family 5 |
| Havana BLAST/BLAT: |
OTTHUMG00000157302 |
| Locus Specific Databases: |
Human Cytochrome P450 (CYP) Allele Nomenclature Committee LRG_579 |