| Catalog number: | GENTAUR-58be5d9099be7 |
|---|---|
| Price: | 2404 € |
| Supplier: | MBS Recombinant Proteins |
| Product name: | Anti-Glucosidase 2 subunit beta, ALEXA Fluor 594 |
| Quantity: | 1000ug |
| Related search: |
| Type: | Conjugated Primary Antibody |
|---|---|
| Conjugated with: | 594, ALEXA FLUOR® |
| Host organism: | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: | Glucosidase 2 subunit beta |
| Specificity: | This antibody reacts specifically with Glucosidase 2 subunit beta |
| Modification: | No modification has been applied to this antibody |
| Modification site: | None |
| Clonality: | Polyclonal Antibody |
| Clone: | Polyclonal Antibodies |
| Concentration: | 1ug per 1ul |
| Antigen Source: | KLH conjugated synthetic peptide derived from human Glucosidase 2 subunit beta |
| Gene ID: | 5589 |
| Applications: | IF(IHC-P) |
| Applications with corresponding dilutions: | IF(IHC-P)(1:50-200) |
| Cross reactive species: | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: | Glucosidase II is an ER-localized enzyme that contains a and b subunits (Glucosidase IIa and Glucosidase IIb) which form a defined heterodimeric complex, Glucosidase IIa is the catalyitc core of the enzyme and can function independently of the b subunit, Glucosidase IIb retains the complete complex in the ER, Glucosidase IIb was first purified from a human carcinoma cell line as a potential substrate for protein kinase C, The phosphorylated form of Glucosidase IIb is localized in the plasma membrane and is highly expressed in FGF-stimulated fibroblasts and epidermal carcinoma cells, The sequence of Glucosidase IIb encodes protein rich in glutamic and aspartic acid with a putative ER retention signal (HDEL) at the C-terminus, Through the HDEL signal at the C-terminus, Trimming of glucoses from N-linked core glycans on newly synthesized glycoproteins occurs sequentially through the action of Glucosidases I and II in the endoplasmic reticulum (ER) |
| Purification method: | Purified by Protein A |
| Storage: | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: | 590nm/617nm |
| Synonyms: | 80 Kda protein, AGE-R2, AGE-binding receptor 2, G19P1, GLU2B_HUMAN, Glucosidase 2 subunit beta, Glucosidase II beta subunit, Glucosidase II subunit beta, Hepatocystin, PCLD, PKCSH, PLD1, PRKCSH, Protein kinase C substrate, Protein kinase C substrate 60, Protein kinase C substrate 80 Kda protein, Protein kinase C substrate 80K-H, 1 kDa protein heavy chain, 80K-H protein |
| Also known as: | Glucosidase 2 subunit beta Antibody |
| Other name: | Anti-Glucosidase 2 subunit beta |
| Advisory: | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: | For facs or microscopy Alexa 1 conjugate |
| Conjugation: | Alexa Fluor |
| Gene target: | Glucosidase 2 subunit beta |
| Short name: | Fluor 594, Anti-Glucosidase 2 subunit beta |
| Label: | ALEXA |
| Alternative name: | ALEXA Fluor 594, antibody to-Glucosidase 2 functionnal sequence b |
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