| Long name: |
ALEXA FLUOR 594 Conjugated, Glucosidase 2 subunit beta Antibody |
| Also known as: |
Anti-Glucosidase 2 subunit beta PAb ALEXA FLUOR 594 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Glucosidase 2 subunit beta |
| Specificity: |
This is a highly specific antibody against Glucosidase 2 subunit beta |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Glucosidase 2 subunit beta |
| Gene ID Number: |
5589 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Glucosidase II is an ER-localized enzyme that contains a and b subunits (Glucosidase IIa and Glucosidase IIb) which form a defined heterodimeric complex, Glucosidase IIa is the catalyitc core of the enzyme and can function independently of the b subunit, Glucosidase IIb retains the complete complex in the ER, Glucosidase IIb was first purified from a human carcinoma cell line as a potential substrate for protein kinase C, The phosphorylated form of Glucosidase IIb is localized in the plasma membrane and is highly expressed in FGF-stimulated fibroblasts and epidermal carcinoma cells, The sequence of Glucosidase IIb encodes protein rich in glutamic and aspartic acid with a putative ER retention signal (HDEL) at the C-terminus, Through the HDEL signal at the C-terminus, Trimming of glucoses from N-linked core glycans on newly synthesized glycoproteins occurs sequentially through the action of Glucosidases I and II in the endoplasmic reticulum (ER) |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
VASAP-60 GIIB |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
594, ALEXA FLUOR®, Alexa Fluor |
| Conjugated: |
Alexa conjugate 1 |
| Gene target: |
Glucosidase 2 subunit beta |
| Short name: |
Glucosidase 2 subunit beta Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 594 |
| Alternative name: |
ALEXA FLUOR 594, Glucosidase 2 functionnal sequence b (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
9411 |
| Gene: |
PRKCSH |
More about : PRKCSH |
| Long gene name: |
protein kinase C substrate 80K-H |
| Synonyms gene: |
G19P1 PCLD PLD1 |
| Synonyms gene name: |
polycystic liver disease |
| Synonyms name: |
advanced glycation end-product receptor 2 glucosidase II beta subunit glucosidase 2 subunit beta hepatocystin |
| Locus: |
19p13, 2 |
| Discovery year: |
1989-06-06 |
| Entrez gene record: |
5589 |
| Pubmed identfication: |
12529853 |
| Classification: |
MRH domain containing EF-hand domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000182029 |