| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
GALNT13/GalNAc-T13 |
| Specificity: |
This antibody reacts specifically with GALNT13/GalNAc-T13 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human GALNT13/GalNAc-T13 |
| Gene ID: |
114805 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
GalNAc-T13 (Polypeptide N-acetylgalactosaminyltransferase 13), GalNAc-T13 may be responsible for the synthesis of Tn antigen in neuronal cells, The N-terminal domain is involved in substrate binding and manganese coordination, With specific expression in the central nervous system, also known as UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 13, is a 556 amino acid protein that displays much stronger enzymatic activity than GalNAc-1 towards GalNAc transfer to mucin peptides such as Muc5a and Muc7, thereby initiating mucin-type O-linked glycosylation in the Golgi apparatus, which is a universal carcinoma marker on malignant cells, while the C-terminal domain is involved in UDP-Gal binding and catalytic reaction, The UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes are substrate-specific proteins that catalyze the transfer of GalNAc (N-acetylgalactosamine) to serine and threonine residues onto various proteins |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
KIAA1918 GalNAc-T13 |
| Also known as: |
GALNT13/GalNAc-T13 Polyclonal Antibody |
| Other name: |
Anti-GALNT13/GalNAc-T13 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
GALNT13/GalNAc-T13 |
| Short name: |
Anti-GALNT13/GalNAc-T13 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-GALNT13/GalNAc-T13 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
23242 |
| Gene: |
GALNT13 |
More about : GALNT13 |
| Long gene name: |
polypeptide N-acetylgalactosaminyltransferase 13 |
| Synonyms gene name: |
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 13 (GalNAc-T13) |
| Synonyms name: |
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 13 polypeptide GalNAc transferase 13 |
| Locus: |
2q23, 1 , 3-q24 |
| Discovery year: |
2003-12-02 |
| GenBank acession: |
AB067505 |
| Entrez gene record: |
114805 |
| Pubmed identfication: |
11572484 12407114 |
| RefSeq identity: |
NM_052917 |
| Classification: |
Polypeptide N-acetylgalactosaminyltransferases |
| Havana BLAST/BLAT: |
OTTHUMG00000131917 |