| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
C-REL Ser503 |
| Specificity: |
This antibody reacts specifically with C-REL (Ser503) |
| Modification: |
Phosphorylation |
| Modification site: |
Ser503 |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic phosphopeptide derived from human C-REL around the phosphorylation site of Ser503 |
| Gene ID: |
5966 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
2007 [PubMed 18037997]), May 2008], NFKB1 (MIM 164011), RELB (604758), These proteins are related through a highly conserved N-terminal region termed the 'Rel domain, a transcription factor that is a member of the Rel/NFKB family, and NFKB2 (MIM 164012), and binding to the NFKB inhibitor (MIM 164008) (Belguise and Sonenshein, dimerization, nuclear localization, which also includes RELA (MIM 164014), ' which is responsible for DNA binding, The REL gene encodes c-Rel, [supplied by OMIM |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
I-Rel c-Rel |
| Also known as: |
C-REL (Ser503) Polyclonal Antibody |
| Other name: |
Anti-C-REL (Ser503) Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
C-REL (Ser503) |
| Short name: |
Anti-C-REL (Ser503) (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-C-v-rel reticuloendotheliosis viral oncogene homolog (avian) (Ser503) (polyclonal) |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
C-Rel, DNA-templated and biological process this GO :0006355 and regulation of transcription, DNA-templated and biological process this GO :0007249 and I-kappaB kinase/NF-kappaB signaling and biological process this GO :0043123 and positive regulation of I-kappaB kinase/NF-kappaB signaling and biological process this GO :0043565 and sequence-specific DNA binding and molecular function this GO :0045084 and positive regulation of interleukin-12 biosynthetic process and biological process this GO :0045087 and innate immune response and biological process this GO :0045893 and positive regulation of transcription, DNA-templated and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :1901215 and negative regulation of neuron death and biological process, REL and IDBG-53133 and ENSG00000162924 and 5966, REL and IDBG-634277 and ENSBTAG00000015386 and 509135, Rel and IDBG-155648 and ENSMUSG00000020275 and 19696, nuclei, sequence-specific DNA binding, this GO :0000980 and RNA polymerase II distal enhancer sequence-specific DNA binding and molecular function this GO :0001205 and RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription and molecular function this GO :0001816 and cytokine production and biological process this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005667 and transcription factor complex and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0006351 and transcription, this GO :0000980 : RNA polymerase II distal enhancer sequence-specific DNA binding, this GO :0000980 : RNA polymerase II distal enhancer sequence-specific DNA binding and also this GO :0001205 : RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription and also this GO :0003700 : sequence-specific DNA binding transcription factor activity and also this GO :0005515 : protein binding and also this GO :0043565 : sequence-specific DNA binding, this GO :0001205 : RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, this GO :0003700 : sequence-specific DNA binding transcription factor activity, this GO :0005515 : protein binding, this GO :0043565 : sequence-specific DNA binding, v-rel reticuloendotheliosis viral oncogene homolog (avian) |
| Identity: |
9954 |
| Gene: |
REL |
More about : REL |
| Long gene name: |
NF-kB subunit , REL proto-oncogene |
| Synonyms gene name: |
v-rel avian reticuloendotheliosis viral oncogene homolog |
| Locus: |
2p16, 1 |
| Discovery year: |
2001-06-22 |
| GenBank acession: |
M11595 |
| Entrez gene record: |
5966 |
| Pubmed identfication: |
1577270 |
| RefSeq identity: |
NM_002908 |
| Classification: |
NF-kappa B complex subunits |
| Havana BLAST/BLAT: |
OTTHUMG00000129418 |